Jan 28, wk 1-D

Question 1

What are the general effects of IL-1 through 6?

Answer 1

Hot T-Bone stEAK

p. 200

Question 2

Explain complement:
activation
actions of molecules

Answer 2

p. 199

Question 3

Describe Syphilis:
Causative agent
Progression of disease
Tests to diagnose

Answer 3

Agent: Treponema pallidum, spirochete

Disease: 3 stages:

• Primary: painless chancre on genitals
• Secondary: systemic, lesions on palms and soles and body, wart-like lesions on genitals ( condylomata lata)
• Tertiary: Gummas (chronic granulomas), neuro syphilis, prostitute’s pupil (accommodates, but doesn’t react to light)
• Congenital: transplacental after first trimester, rhagades (linear sores at corners of mouth), snuffles (nasal discharge), notched teeth, CN VIII deafness

Tests: FTA-ABS best test, VDRL/RPR are serological tests that are nonspecific, but can work