24 May wk9-B

Question 1

What is variola?

Answer 1

Small pox

Question 2

How is Small pox spread?

Answer 2

Respiratory droplets? Face to Face and close contact

Question 3

What is the presentation of small pox?

Answer 3

Incubation period of 10 or more days
Prodromal high fever that subsides after several days and also has headaches, malaise, pharyngitis, abd pain and vomiting
Rash several days after prodrome that covers face the trunk, and extremities, and includes mucous membranes; mucosal lesions rupture quickly and spread virus, cutaneous lesions are ~4mm and are umbilicated in the center
Lesions eventually confluent and scab over

Question 4

How do Heparin and Aldosterone interact?

Answer 4

Heparin is known to inhibit the actions of Aldosterone and will therefore cause hyperkalemia and metabolic acidosis

Question 5

What are likely adverse effects of long-term heparin therapy in an elderly individual?

Answer 5

Osteoporosis and alopecia

Heparin stimulates the release of G-CSF from osteoblasts that works with RANKL to stimulate the genesis of osteoclasts

Question 6

What is beclomethasone?

Answer 6

Steroid that comes in many forms but is often inhaled and used to control asthma exacerbation

Question 7

What are some of the long-term effects of uncontrolled asthma?

Answer 7

Can eventually lead to smooth muscle hypertrophy and overgrowth of goblet cells that can lead to mucous plugging and fibrosis and irreversible airway remodeling

Question 8

What are some common side effects of inhaled steroids?

Answer 8

Oral candidiasis from immune suppression

Dysphonia (hoarseness)

Question 9

Why are long-term systemic steroid treatments tapered when discontinued?

Answer 9

Tapering prevents adrenal insufficiency assumedly by allowing time for it to ramp up production after being low from decreased ACTH stimulation

Question 10

What is the triad of Sx with mononucleosis?

Answer 10

Sore throat, fever, LAD