ISCE cards Flashcards
STEMI
Ix - ECG, FBC, LFTs, U&Es, lipids, troponin, D dimer (if chest pain non-specific), blood pressure
Mx - A-E approach. Call senior. Give 300mg aspirin. Refer to cardiology. If PCI available, do within 2 hours. If not available, give ticagrelor and aspirin for fibrinolysis.
Secondary prevention: aspirin + clopidogrel. Lifestyle changes. ACEi, beta blocker, statin.
NSTEMI
Ix - ECG, FBC, LFTs, U&Es, lipids, troponin, D dimer (if chest pain non-specific), blood pressure.
Mx - A-E approach, call senior/cardiology. Give ticagrelor and aspirin. If unstable, will need angiography to investigate if PCI needed.
Secondary prevention: aspirin + clopidogrel. Lifestyle changes. ACEi, beta blocker, statin.
Acute heart failure
Mx - IV loop diuretics
O2
Nitrates (only give if cardiac ischaemia and not hypotensive)
CPAP (if in resp failure)
If in cardiogenic shock:
- dobutamine
- ventricular assist
- noradrenaline
Chronic heart failure
Ix - Pro-BNP, lipids, blood gas?, FBC, LFTs, U&Es, ECG
Mx - 1st line: ACEi + beta blocker
- 2nd line: aldosterone/mineralocorticoid antagonist
Both options increase K+ so monitor
Peri-arrest bradycardia
Mx
1st - IV atropine 500mcg up to 3g max
2nd - transcutaneous pacing
3rd - isoprenaline/adrenaline infusion
Peri-arrest tachycardia
Mx
3x DC shocks
If no improvement:
- Broad complex: if irregular needs underlying cause treated. If regular give loading dose amiodarone and 24hr infusion.
- Narrow complex: If irregular likely AF so give beta blockers or cardiovert if less than 48 hours. If regular do vagal manoeuvres followed by adenosine.
Pericarditis
Ix - ECG (saddle-shaped ST elevation, PR depression), transthoracic echo, inflammatory markers, troponin
Mx - admit if unstable or feverish. Avoid physical exertion. Give NSAIDs and colchicine.
Aortic dissection
Ix - chest XR, CT angio, tranoesophageal echo, lactate, FBC, U&Es, LFTs.
Mx - A-E assessment, call vascular surgeons. Analgesia, control blood pressure. Potentially need surgery.
Infective Endocarditis
Ix - blood culture, FBC, CRP, U&Es, LFTs, obs, ECG, urine dip, transthoracic echo
Mx - IV abx, surgical valve replacement
Angina
Ix - FBC, CRP, ECG, exercise-stress ECG
Mx - aspirin + statin. lifestyle changes. Sub-lingual GTN. Beta blocker and/or calcium channel blocker (NOT VERAPAMIL)
AF
Ix - ECG (can offer ambulatory if coming and going), FBC, CRP, LFTs, U&Es, obs, clotting, TFTs
Mx - assess A-E if unstable. If <48hrs can be cardioverted. Beta blocker/calcium channel blocker/digoxin for rate control. Offer DOAC depending on clot risk.
Hypertension
Ix - clinic BP, ambulatory BP, investigate for potential underlying cause
Mx - If signs of end-organ damage -> hospital admission for specialist management. Otherwise:
ACEi/ARB for most under 55s
Amlodipine for over 55s or under 55s of Afro-Caribbean heritage
If still raised then above can be used in combination
If still raised indapamide can be added
Acute exacerbation of COPD
Ix - ABG, Chest XR, sputum culture, FBC, CRP
Mx - A-E approach. Call senior help. Oxygen therapy, Salbutamol neb. Ipratropium bromide if no improvement. Oral steroids should be given for all exacerbations. Non-invasive ventilation is the last line.
Asthma attack
Ix - peak flow, ABG, chest XR, FBC, CRP
Mx - Assess A-E. Oxygen. Salbutamol nebs. Oral/IV steroids. Ipratropium bromide if no improvement. Call senior help. Single dose IV MgSO4. Abx if evidence of infection.
Pulmonary Embolism
Ix - Wells score, CTPA, chest XR, D dimer
Mx - DOAC in stable patients. If unstable, thrombolysis should be given. Oxygen therapy can be given if desaturated. Call for senior help.
Pneumonia
Ix - CURB-65, Chest XR, sputum sample, legionella urinary antigen (if high risk), FBC, CRP, blood gas, U&Es
Mx - if severe, A-E approach, call senior, start sepsis 6 protocol. In community, manage with amoxicillin
Pneumothorax
Ix - chest XR, FBC, D dimer, troponins if associated chest pain, ECG
Mx - if less than 2cm air then conservative mx. If more than 2cm then aspirate, if not successful then insert chest drain. Lifetime ban from scuba diving, smoking should be discouraged to prevent recurrence. Can fly again 1 week post check up XR
Pleural Effusion
Ix - chest XR, FBC, D dimer, troponins if associated chest pain, ECG, USS, CT (to look for underlying cause)
Mx - aspiration (can also be investigated for cause), sepsis 6 if concerned
COPD
Ix - peak flow, spirometry, Chest XR, FBC
Mx - smoking cessation, pneumococcal vaccine, annual influenza vaccine, pulmonary rehab. SAMA/SABA is 1st line. If worsening must determine if asthmatic features:
W/ asthmatic features: start LABA + ICS. If still not effective, add LAMA for triple therapy.
W/o asthmatic features: LABA + LAMA
Asthma
Ix - peak flow, spirometry, FeNO testing
Mx - 1st line: SABA
2nd line: SABA + low dose ICS
3rd line: SABA + ICS + LTRA
Bronchiectasis
Ix - peak flow, spirometry, CT
Mx - physical training (e.g. inspiratory muscle training), postural drainage, antibiotics for exacerbations, immunisations
Lung cancer
Ix - chest XR, bronchoscopy, CT, EBUS, FBC, LFT, bone profile, U&Es
Mx - chemo/radio/surgery
Pulmonary fibrosis
Ix - peak flow, spirometry, chest XR, ANA +ve, FBC, U&Es
Mx - pulmonary rehab, O2 therapy
TB
Ix - Mantoux test (latent TB), sputum smear, sputum culture, chest XR, NAAT (rapid test)
Mx - Active TB: rafampicin, isoniazid, ethambutol, pyrazinamide for 2 months. Rifampicin and isoniazid for further 4 months.
Latent: 3 months isoniazid + rifampicin. OR 6 months of pyrazinamide
Ectopic Pregnancy
Ix - vital signs, pregnancy test, FBC, LFTs, U&Es, CRP, TVUSS
Mx - If unstable take ABCDE approach. Refer gynae. If embryo <35mm, unruptured, asymptomatic, no heart beat and low hcg then expectant management. If <35mm, unruptured, no heart beat and low HCG then can be treated with methotrexate. In all other cases should be treated surgically. Give analgesia.
If compromised fertility can opt for salpingotomy as opposed to salpingectomy.
Cholangitis
Ix - LFTs, U&Es, FBC, CRP, USS
Mx - Refer gastro. Analgesia. IV abx, ERCP
Acute hepatitis
Ix - FBC, U&E, CRP, LFTs, hepatitis serology
Mx - A - no tx
B - antivirals
C - antivirals
D - none
E - none
Bowel obstruction
Ix - FBC, CRP, LFTs, U&Es, lactate, abdo XR, abdo CT,
Mx - Refer surgeons. Analgesia. NBM, IV fluids, nasogastric tube, surgery, (if risk of perf give abx)
Appendicitis
Ix - FBC, U&E, LFTs, CRP, lactate, pregnancy test, urinalysis, USS, CT if clinical doubt
Mx - ABCDE approach. Refer gastro surgeons. Analgesia. Appendicectomy
Pancreatitis
Ix - FBC, U&Es, LFTs, CRP, amylase, lipase, USS/contrast CT to look for underlying cause
Mx - Fluid resuscitation, measure urine output, analgesia, attempt oral intake but if not possible then nasogastric tube can be used, abx if infective picture.
Peritonitis
Ix - FBC, U&Es, LFTs, CRP, cultures, paracentesis
Mx - cefotaxime
Variceal haemorrhage
Ix - endoscopy, FBC, LFTs, lactate, clotting, group and save
Mx - ABCDE approach. Call for senior help. Terlipressin and abx. Treated using endoscopic management.
Ovarian torsion
Ix - pregnancy test, FBC, U&Es, LFTs, CRP, TVUSS
Mx - Analgesia, refer gynae, diagnostic/treatment laparotomy.
Testicular torsion
Ix - thorough examination. FBC, U&Es, STI screen, LFTs, CRP, urinalysis
Mx - analgesia. Refer urology for urgent surgical exploration.
Epididymo-orchitis
Ix - thorough examination. FBC, U&Es, STI screen, LFTs, CRP, urinalysis
Mx - depends on cause. Treat underlying infection ie, STI/UTI
AAA
Ix - vital signs, FBC, group and save, lactate. CT if stable enough
Mx - urgent senior help. Urgent referral to vascular surgeons.
Endometriosis
Ix - FBC, CRP, STI screen if indicated, TVUSS, diagnostic laparotomy
Mx - NSAIDS/paracetamol. COCP, progestins. If no improvement a GnRH analogue may be an option, or surgical removal of endometrial tissue from the abdomen.
PID
Ix - FBC, urinalysis, STI screen, high vaginal swab, pregnancy test
Mx - abx and analgesia
IBD
Ix - FBC, stool culture, CRP, U&Es, LFTs, foecal calprotectin, tissue transglutanimase, endoscopy, colonoscopy and biopsy,
Mx - Medical: mesalazine, steroids, biologics
Surgical: colectomy
IBS
Ix - FBC, ESR, CRP, tTG, ?colonoscopy if significant concern
Mx - antispasmodics, laxatives/loperamide depending on stool symptoms, FODMAP diet
Coeliac disease
Ix - tissue transglutaminase, IgA, endoscopic intestinal biopsy
Mx - gluten-free diet
Diverticular disease
Ix - FBC, CRP, LFTs, U&Es, FIT, colonscopy, CT
Mx - analgesia. Increase dietary fibre. Mild flairs can be treated with abx. Abscesses or recurrent flairs can be treated with surgeries.
Haemorrhoids
Ix - examination
Mx - increase dietary fibre, laxatives, local anaesthetic/steroid creams, surgery for large haemorrhoids
Peptic ulcer
Ix - H.pylori test, stool sample, FBC,
Mx - PPI, abx if H.pylori +ve
GORD
Ix - CRP, endoscopy, ECG
Mx - PPI, diet modification if known triggers
post partum haemorrhage
Ix - vital signs, group and save, FBC, clotting
Mx - Assess A-E, call senior help. oxytocin/syntometrin, 2 large bore resus cannulae, warmed fluids, blood transfusion, oxygen, catheterise
Miscarriage
Ix - speculum examination, TVUSS, beta HCG, rhesus status, group and save, FBC, vital signs
Mx - Expectant management can be attempted if haemodynamically stable. If expectant management unsuccessful, can be managed medically using misoprostol. If still unsuccessful or if haemodynamically unstable, can be managed surgically.