IRAT Exam 1 Questions Flashcards
Which type of research deals with the areas of inquiry like pharmacology, medical chemistry, pharmaceutics?
Applied
_________ refers to the collection of information based on human experience?
Empiricism
Which of the following is not among the criteria that need to be met for an IRB application to be approved?
There is no potential harm to the patients.
What stage of the drug development process is about determining the tolerable dose?
Phase 1
Equitable selection is based on which ethical principle?
“Justice, because the risks of research should be shared equally.”
A scientific study designed to test a medical intervention in humans is known as:
A clinical trial
A study’s ________ measures the capacity to detect a difference in the study groups if a true difference exists.
Power
The ___________ of an event is calculated as a ratio between two incidence proportions or two incidence rates.
Relative Risk
_______________ reflects the extent to which the clinical outcome of interest (dependent variable) in a study is caused by the treatment (independent variable).
Internal Validity
Which of the following observational study designs observe study participants at only one point in time?
Cross-sectional study design
Which of the following is considered to be the gold standard in evaluating the safety and efficacy of an intervention?
Randomized clinical trials
Which study design is universally superior to other study designs?
None of these answers are correct
Which of the following sampling strategies has the best possibility to result in a representative sample or participants from a source population?
Random sampling
Cohort studies mirror the clinical trial design in the following way:
They start with groups exposed and un-exposed
A major difference between a case series and case report is:
The sample size
