invasive scc of penis Flashcards
distribution is most at the __ and least where
Risk actors: Lack o circumcision, poor penile hygiene, phimosis (25 to 75%), low socioeconomic status, HPVin ection (15 to 80%), UV-radiation exposure, tobacco use.
■ Demography:More common in developing nations (up to 10%o cancers in men;rare in industrial- ized nations).
■ Precancerous lesion/disorders: Phimosis, chronic balanoposthitis, pseudoepitheliomatous keratotic and micaceous balanitis, lichen planus, lichen sclerosus, giant condyloma, and HPV-induced IN.
■ Symptoms:Precursorlesion,itching/burning under oreskin,ulceration o glans,orprepuce.
■ Clinical ndings:Subtleinduration;smallexcrescence;smallpapule;wartygrowthtoanobviousextensive
carcinomawithsloughing.Necrosisand/orsecondaryinectioninphimotic oreskin.Extendsalongthe
penileshatandinvolvescorporacavernosa.Rarely,bleeding,urinary stula,andurinaryretentionoccur.
■ Distribution: Glans (48%), prepuce (21%), glans and prepuce (9%), prepuce glans and sha t (14%),
coronal sulcus (6%), sha t (< 2%).
■ Metastasis:Inguinallymphnodemetastases;distantsitesrare.
