GENITAL(PENILE/VULVAR/ANAL)LENTIGINOSES

Question 1

onset
manif
sites
course

Answer 1

Onset:Adulthood.
■ Clinical ndings:Tan,brown,intenseblue-black;usuallyvariegated,5-to15-mmmacules.
■ Sites: In clusters on vulva (labia minora, Fig. 34-7), penis (glans, sha t) (Fig. 34-8), and perianal areas.
■ Course: Persist or years without change in size

Question 2

histology

Answer 2

Histology: No signi cant melanocytic hyperplasia; nevus cells are not present; pigmentation is caused
by increased melanin in basal cell layer

Question 3

diagnosis

Answer 3

Diagnosis:Dermoscopyrulesoutinsitumelanoma;histologycon rmsdiagnosis.
■ Extensive lesions that cannot be easily removed should be ollowed photographically; areas that
show signi cant change should be biopsied.