Introduction to Virology - Deluca

Question 1

What components make up a virion?

Answer 1

Genome (either RNA or DNA), surrounded by a protein shell called a capsid, and sometimes coated in a lipid envelope.

Question 2

Ways to visualize viruses?

Answer 2

Electron microscopy, Cryo EM, and X-ray crystallography

Question 3

What percentage of people are infected with herpes viruses?

Answer 3

About 70-90%

Question 4

Which virus was used to track human evolution?

Answer 4

JC Virus (Human Polyoma)

Question 5

Classical System of Virus Classification

Answer 5

Describes the nucleic acid type, symmetry of the capsid, presence of an envelope, and dimensions of the virion.

Question 6

Baltimore System of Virus Classification

Answer 6

Describes the pathways by which viruses with different genomes make mRNA.

Question 7

Requirements of the Infectious Cycle (Propagation)

Answer 7

1. Viruses are packaged in particles which facilitate entry into cells.
2. The genome encodes information for initiating and completing the infectious cycle.
3. Establishment in the host population

Question 8

Describe Cytopathic Effects

Answer 8

Observable changes in the morphology of cultured cells as a consequence of viral infection.