Introduction to pharmacology Flashcards
pharmacokinetics
what the body does to the drug
pharmacodynamics
what the drug does to the body
pharmacology
the study of drugs
examples of covid drugs
dexamethasone
hydroxychoroquine
ivermectin
remdesivir
tocilizumab
excipients
the other components within drugs
drug family mab
monoclonal antibody
adalimumab
drug family lol
beta blockers
ticagrelor
drug family vir
anti-viral
aciclovir
drug family Caine
local anaesthetic
lidocaine
cocaine
drug family ine
active principles
morphine
alkaloid chemistry
active principle isolated from a plant
drug family tide
peptide
drug family prazole
proton + benzimidazole
proton pump inhibitor
lansoprazole
morphine
active principle in opium
atropine
from belladonna
nicotine
from tobacco
coniine
from hemlock
caffeine
from coffee
cocaine
from coca
quinine
from cinchona
synonym for health
physiology
synonym for disease
pathology
synonym for treatment
pharmacology
drug effects are what dependent
concentration
clinical effects are what dependent
dose
categories that drugs fall into
natural
semi-synthetic
endogenous
synthetic
recombinant
types of receptors
G-protein coupled GPCR= 7 transmembrane receptors 7TM
nuclear hormone receptors
catalytic receptors
ion channels
ligand-gated ion channels
voltage-gated ion channels
transporters
ATP-binding cassette ABC
ATPases
Solute carriers SLC
4 categories to understand pharmacology
chemistry
pharmacology
physiology
clinical
what does the chemistry show
just the family of drug
what does the pharmacology show
the target of the drug and its activity
what does the physiology show
the physical action of the drug in the body
what does clinical show
the generic idea
e.g. lidocaine is a local anaesthetic
mechanism of drug action
pharmacology is the primary MoDA: ligand-activity-target
physiology is the secondary MoDA: functional effects