Introduction to Immunology Flashcards

1
Q

__ is defined as a balanced state of having adequate biological defenses to fight infectious disease or other unwanted biological invasion while having adequate tolerance to avoid allergy and auto immune diseases.

a. Immune system
b. Immunity
c. Immune response
d. None of the above

A

b. Immunity

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2
Q

The co- orginated reaction of these cells and molecules to infectious microbes is known as which of the following?

a. Immune system
b. Immunity
c. Immune response
d. None of the above

A

c. Immune response

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3
Q

The collection of cells, tissues and molecules that protects animals against microbial invasion essential for life is referred to as ___.

a. Immune system
b. Immunity
c. Immune response
d. None of the above

A

a. Immune system

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4
Q

Which of the following is not a function of the immune system?

a. Prevent infections and eradicate estabilished infections by recognizing and eliminating foreign antibodies
b. Formation of immunological memory
c. Development of tolerance to self antigens
d. All the above are true

A

a. Prevent infections and eradicate estabilished infections by recognizing and eliminating foreign antibodies

**eliminating foreign antigens

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5
Q

Which of the following is false regarding innate immunity?

a. It is nonspecific and is present from birth
b. It is acquired later on in life to fight against specific invaders
c. It is the initial and rapid response to pathogens that have damaged tissue
d. Encompasses protective factors present in an individual animal independent of antigenic stimulus

A

b. It is acquired later on in life to fight against specific invaders

**adaptive immunity is acquired, innate is present at birth

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6
Q

Which of the following is false regarding adaptive immunity?

a. It can be acquired passively by placental transfer or injection of specific antibodies
b. It can be acquired actively by infection or vaccination
c. It is nonspecific against specific invaders
d. Passive immunity will last until the antibodies die whereas active immunity will last depending on the antigen

A

c. It is nonspecific against specific invaders

**it is specific and defends against specific invaders

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7
Q

True/False: Adaptive immunity relies on innate immunity.

A

True

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8
Q

True/False: Only adaptive immunity has cellular and humoral responses.

A

False

**Innate and adaptive have cellular and humoral responses

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9
Q

Which of the following is false?

a. Phagocytes like neutrophils and macrophages are cellular respones to signs of inflammation for innate immunnity
b. Cytotoxic T lymphocytes are cellular responses used for adaptive immunity
c. Complement, lysozyme, C reactive proteins and antiviral interferon are humoral respones for innate immunity
d. B cells secreting antibodies, and mast cells are humoral responses used for adaptive immunity

A

d. B cells secreting antibodies, and mast cells are humoral responses used for adaptive immunity

**mast cells are cellular respones for innate immunity along with NK cells and Dendritic cells

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10
Q

True/False: With passive immunity we produce the anitbodies when we have been exposed to an antigen.

A

False

**active immunity we produce the Ab’s and with passive its passed from the mother

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11
Q

What is a naturally acquired antibody?

A

Exposure to an actual disease causing organism/ antigen that your body fought and now remembers

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12
Q

True/False: Passive immunity antibodies will last a lifetime.

A

False

**antibodies from mother will protect the baby for a short period of time while the immune system develops in the bone marrow and thymus

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13
Q

True/False: A booster shot is considered an as an active immunity.

A

True

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14
Q

A planned exposure to a form of an antigen that has been killed or weakened - you detected it, eliminated it, and remembered it. This is referred to as an ___ __ antibody.

A

Artificially acquired Ab

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15
Q

True/False: Most microorganisms do not cause disease in humans and animals its pathogens such as protozoa, bacteria, viruses, fungi, and worms that casue disease.

A

True

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16
Q

What are the three components that make up both humans and pathogens?

A

Proteins
Carbs
Lipids

17
Q

How does the immune system distinguish pathogens from human and animal tissues?

A

By discriminating between self and non-self proteins and detecting danger signals such as non-apoptotic necrotic cell death

18
Q

Which of the following is fasle regarding pattern recognition receptors (PRRs)?

a. Expressed on macrophages and dendritic cells to sense the presence of pathogens
b. Recognize pathogen- associated molecular patterns (PAMPS) on diverse classes of microbes
c. Used by adaptive immune cells to recognize non-self proteins
d. Found on the plasma membrane

A

c. Used by adaptive immune cells to recognize non-self proteins

**used by innate immune cells

19
Q

Which of the following is not a function of PRRs?

a. Recognition and binding to PAMPS
b. Phagocytosis by the host cell
c. Promotes recruitment of leukocytes to site of infection
d. All the above are functions of PRRs

A

d. All the above are functions of PRRs

20
Q

Which of the following PRR’s is found within the cytoplasm and recognize double stranded viral DNA?

a. Mannose receptors
b. Toll-like receptors (TLR)
c. NOD-like receptors (NLR)
d. RIG-like helicases (RLH)

A

d. RIG-like helicases (RLH)

21
Q

Which of the following are expressed by macrophages and initiates the complement cascade?

a. Mannose receptors
b. Toll-like receptors (TLR)
c. NOD-like receptors (NLR)
d. RIG-like helicases (RLH)

A

a. Mannose receptors

22
Q

Which of the following can be activated by double stranded RNA?

a. Mannose receptors
b. Toll-like receptors (TLR)
c. NOD-like receptors (NLR)
d. RIG-like helicases (RLH)

A

b. Toll-like receptors (TLR)

23
Q

Which of the following can lead to the production of cytokines when activated?

a. Mannose receptors
b. Toll-like receptors (TLR)
c. NOD-like receptors (NLR)
d. RIG-like helicases (RLH)

A

c. NOD-like receptors (NLR)

24
Q

Which of the following binds flagellin and bacteria DNA and can be activated by bacterial lipopeptides and peptidoglycan?

a. Mannose receptors
b. Toll-like receptors (TLR)
c. NOD-like receptors (NLR)
d. RIG-like helicases (RLH)

A

b. Toll-like receptors (TLR)

25
Q

True/False: Innate immune responses operate independently of adaptive immune responses.

A

True

26
Q

Passive immunity is characterized by all the following except:

a. It can be transferred from an immune animal to a naive animal via serum
b. It provides immediate protection
c. It provides long term protection
d. It is of benefit both prophylactically and therapeutically

A

c. It provides long term protection

27
Q

Cells of the adaptive immune response include all of the following except:

a. Natural killer cells
b. T lymphocyte
c. B lymphocyte
d. None of the above

A

a. Natural killer cells