Introduction to Histopathology (M)

Question 1

What are the Greek words that comprises the term histopathology?

Answer 1

1) Histo: means tissue
2) Patho: means disease
3) Logy: means study

Question 2

What is histopathology?

Answer 2

It is the branch of biology w/c deals w/ the study of diseased tissue under microscope

Question 3

What is histology?

Answer 3

It is the study of normal tissue

Question 4

What is biopsy?

Answer 4

It is the process of removal of a bit of tissue from living being

Question 5

What is autopsy?

Answer 5

It is the process of removal of large tissue / organ from a dead body

Question 6

What is the mechanism of autolysis?

Answer 6

It is the destruction of tissue due to its own enzymes

Question 7

What is the mechanism of putrefaction?

Answer 7

It is the destruction of tissue due to the environmental bacteria & microorganisms

Question 8

What are the purposes of histopathology?

Answer 8

1) To diagnose stage of cancer
2) To diagnose pre-cancer stage
3) To diagnose other inflammatory diseases

Question 9

Why do we need to study histopath?

Answer 9

To determine the abnormal from normal tissue

Question 10

*What are the markers of the determination of abnormal tissue from normal tissue?

Answer 10

Accdg to:

1) Cell size
2) Cell shape
3) Nucleus to cytoplasm ratio

Question 11

What is the characteristic of a normal cell?

Answer 11

Its cytoplasm is bigger > nucleus

Question 12

What is the characteristic of a cancer cell?

Answer 12

Its cytoplasm is shorter > nucleus

Question 13

What is the flow in the histopath lab?

Answer 13

1) Starts in the operating room (OR)
2) Then sx collection
3) Sx receiving
4) Entering of sx details
5) Charging of requested procedure
6) Processing of sx
7) Then reading done by patho

Question 14

What are the aspects that should be considered along w/ sx collection?

Answer 14

1) Accurate pt identification
2) Orientation of sxs
3) Adequate fixation

Question 15

Who is the professional that does sx collection along w/ the aspects associated w/ it that should be considered?

Answer 15

OR staff

Question 16

What are the aspects that should be considered w/c are associated w/ sx receiving?

Answer 16

1) Sx acceptability

2) Completeness of request

Question 17

Who are the professionals that does the charging of requested procedure?

Answer 17

1) Histotechnician
2) Laboratory clerk
3) Medical technologist (/ medtech staff)

Question 18

What are the aspects that should be considered w/c are associated w/ processing of sx?

Answer 18

1) Proper embedding technique
2) Microtomy
3) Staining
4) Avoiding unacceptable artifacts

Question 19

Who are the professional that do the processing of sx along w/ the considerations of the aspects associated to it?

Answer 19

1) MT staff

2) Histotechnician

Question 20

What are done by the patho?

Answer 20

1) Inspection of controls

2) Slides reporting