Introduction Flashcards

1
Q

what is an infection

A

invasion of a host’s tissues by micro-organisms

diseases caused by toxins, multiplication of microbes or the host response

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2
Q

why can people have pathogens within then but not be affected?

A

the pathogens are in areas that are ok but they may move to places that are not ok

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3
Q

what are zoonotic diseases

A

diseases spread by animals e.g. Rabies and Anthrax

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4
Q

what are microbiota

A

bacteria that exist on or in you which are normally harmless or beneficial

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5
Q

when can microbiota become harmful

A

when they transfer to other sites in the body

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6
Q

give 4 ways in which people become infected

A

physical contact, airborne, ingestion of contaminated food/water or vectors

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7
Q

what is the vector for the spread of malaria

A

mosquito

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8
Q

what are the 2 ways of transmissions of how people get infected

A

horizontal and vertical

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9
Q

what are the 3 methods in which people become infected in the mode of horizontal transmission

A

contact (direct/indirect)
inhalation
ingestion (faecal-oral transmission)

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10
Q

what is vertical transmission

A

transmission of an infection from mother to child, before or at birth

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11
Q

what should you ask when taking a patient history for a suspected infection

A

ask about symptoms (severity and duration) and potential exposures (where they’ve been, animals they’ve been in contact with)

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12
Q

what do supportive investigations find out

A

how unwell the patient is

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13
Q

why do you repeat supportive investigations over periods of time

A

to find out if the patient is getting better or worse

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14
Q

give some example of supportive investigations

A

full blood count, C reactive protein test, imaging, liver and kidney function tests

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15
Q

what tests are undertaken to find out the cause of an infection

A

bacteriology and virology tests

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16
Q

what are virulence factors

A

molecules produced by pathogens

17
Q

what are exotoxins

A

a type of virulence factor that is produced as part of their pathogenic process

18
Q

what are endotoxins

A

structures in pathogen (e.g on the bacteria cell wall) that cause a response by the host

19
Q

what is dissemination

A

spreading of the pathogen in the body

20
Q

what is cellulitis

A

severe inflammation of dermal and subcutaneous layers of the skin

21
Q

what 2 bacteria are the most common causes of cellulitis

A

streptococcus and straphylococcus

22
Q

what is tested for in a full blood count

A

white blood cell, white blood cell differential, red blood cell, haemoglobin, haematocrit, platelet and mean corpuscular volume

23
Q

what is the mean corpuscular volume

A

average size of your red blood cells

24
Q

why are agar plates red

A

they are a spread of blood

25
Q

what is chocolate agar

A

spread of lysed red blood cells

26
Q

will all bacteria grow on agar plates

A

no, but most will

27
Q

what 3 methods of virus detection are there?

A

antigen detection for the virus or patients response and detecting viral DNA or RNA

28
Q

what methods of bacteria detection are there?

A

get specimen samples, look at specimen under microscopy, culture bacteria and test antibiotic susceptibility. use antigen or nucleic acid detection