Intro to Physiology and Homeostasis Flashcards
Organisation of Human Body
Cells –> Tissues –> Organs –> Systems
Integration of Human Body Functions
Body systems work together as a integrated unit to maintain a healthy body
The normal body function requires coordination of function from molecular and cellular to whole body function
To remain healthy, the human body must maintain highly regulated optimum physiological condiitons
Homeostasis
Maintenance of stable internal environment within the body by coordinated physiological mechanisms
Regulated within a narrow range
Apply Knowledge to Homeostasis
- Core concept in health and disease
- Disruption of homeostasis –> disease or death
Physiology of Cell Membrane
Much control occurs at level of membrane
Change in membrane potential is central to functionality of nerve and muscle cells
Pharmacological agents
Intrinsic Controls
Local controls within an organ
Extrinsic Controls
Regulatory mechanisms initiated outside an organ
Accomplished by nervous and endocrine system
Feedforward Feedback
Responses made in anticipation of a change
I.e. Responding to cold weather by shivering
Positive Feedback
Amplifies an initial change
I.e. Oxytocin from Posterior pituitary
Negative Feedback
Opposes an initial change
I.e. Blood sugar regulation, Core Body Temp, MABP, Blood Gases, Blood pH
Primary type of homeostatic control mechanisms within the body
Promote stability by regulation of physiological variable within a narrow range
Negative Feedback Control System
Deviation in Regulated Variable –> Sensor –> Control Centre –> Effectors –> Compensatory response –> Restoration of regulated variable to desired range –> Reduction of stimulus