Intro to Hepatitis Viruses

Question 1

Are hepatitis viruses closely evolutionarily related to each other?

Answer 1

no

Question 2

What is similar among hepatitis viruses?

Answer 2

symptoms

all infect hepatocytes

Question 3

Which hepatitis viruses can cause acute infections? How are these treated?

Answer 3

all of them

supportive care

Question 4

What is the transmission route of hepatitis A?

Answer 4

fecal-oral

Question 5

What are the transmission routes of Hepatitis B and C?

Answer 5

sex
birth
blood

Question 6

What are the serology diagnoses for Hep A?

Answer 6

IgM = acute
IgG = recovered/vaccinated

Question 7

What is the serology diagnoses for Hep B?

Answer 7

• viral surface antigen = acute

- IgG against viral surface antigen = recovered/vaccianted

Question 8

What are the serology diagnoses for Hep C?

Answer 8

EIA = real or false +
RIBA = confirmation

Question 9

What can acute infection with Hep B And C lead to?

Answer 9

cirrhosis and/or cancer

Question 10

How is cirrhoses or cancer, caused by acute Hep B/C, treated?

Answer 10

polymerase inhibitors + IFN

Question 11

What are the problems with polymerase inhibitors + IFN used to treat cirrhoses or cancer, caused by acute Hep B/C?

Answer 11

side effects

often ineffective

Question 12

What two classes of drugs are replacing treatment of cirrhoses or cancer, caused by acute Hep B/C, with polymerase inhibitors + IFN?

Answer 12

• first gen protease inhibitors (for serotype 1)

- second gen antivirals

Question 13

_______ and uncertain _______ for chronic Hep B&C invites competition from _______ medicine

Answer 13

grueling treatment
prognosis
alternative

Question 14

What must be taken into account if using alternative medicine to treat chronic Hep B&C?

Answer 14

what patient is doing and consuming

is it happening with or instead of prescribed treatment