intro Flashcards
what is the atopic triad
asthma, alelrgies, atopic dermatitis
how to describe skin lesions (5)
- palpability
- color
- texture
- size
- location
flat lesion under 1 cm in diameter
macule
flat lesion >1 cm in diameter
patch
raised, solid lesion under 1 cm
papule
raised solid lesion >1 cm
nodule
raised solid lesion >2 cm
tumor
raised solid lesion >1 cm, flat topped, plateau
plaque
raised, clear fluid filled lesion under 1 cm
vesicle
raised, clear fluid filled lesion > 1 cm
bulla
raised, pus fluid filled lesion
pustula
round or flat topped edematous and erythematic lasting under 48 hrs, migratory, pruritic
wheals
enlarged superficial blood vessels, blanchable
telangiectasia
loss of epidermis
erosion
flake or plates of skin
scale
erosion and scale are examples of what type of skin lesions
secondary
secondary skin lesion; dried plasma or exudate
crust
secondary skin lesion; complete loss of epidermis partial/complete dermis; heals with scar
ulcer
traumatized or abraded skin usu due to rubbing
excoriation
exagerrated scar, beyond wound edges
keloid
plaque covering ulcer
eschar
place these in order from largest to smallest: purpura, petechiae, ecchymoses
ecchymoses > purpura > petechiae
hypopigmented macules & patchhes with fine scale; wood’s light showing orange yellow hue
tinea versicolor
MOA topical steroids
inhibits NK-kappa B–>suppresses both B and T cell fxn
allylamines and benzylamines are better for dermatophytes or candida?
dermatophytes
polyenes are better for dermatophytes or candida?
candida
nystatin is in what class?
polyenes
nafitifine is in what class?
allylamines and benzylamines
imidazoles are fungistatic or fungicidal
fungistatic
azoles inhibit what?
14 alpha demethylase (conversion of lanosterol to ergosterol)
allyamines inhibit what?
squalene epoxidase
which drug SE: antiandrogen, liver toxicity, p450 inhibitor
azoles
which drug SE: taste deficiency, liver toxicity, HA, GI effects
allylamines and benzylamines
first generation H1 antag (3)
- diphenhydramine
- hydroxyzine
- chlopheniramine
2nd gen H1 antag (3)
- cetirizine
- loratidine
- fexofenadine
are 1st or 2nd generation H1 antag known to be sedating
1st generation
tx of psoriasis (3)
- coal tar
- tazarotene
- vitamin D analogs
most specific Ab for lupus (2)
- anti-dsDNA
2. anti-smith
tx of lupus
steroids, immunosuppressants