INTRACELLULAR ACCUMULATION

Question 1

Define Metabolic Derangement?

Answer 1

Slide 68

Question 2

Name two categories of intracellular accumulation?

Answer 2

Slide 68

Question 3

What ate the causes of intracellular accumulation?

Answer 3

Slide 69
1. Abnormal or inadequate metabolism - fatty changed
2. Abnormal exogenous substances - silica or carbon particles
3. Abnormal endogenous substances-degenerof CNS disease

Question 4

Triglycerides accumulation is most commonly found in?
Reversible but cause_____________ and ____________

Answer 4

1. Liver,heart,mm & kidney
2. Inflammation and fibrosis

Question 5

Cholesterol is used for?
Accumulation of cholesterol is seen in?

Answer 5

1. Synthesis of cell membrane
2. Intracytoplasmic vacoules causes atherosclerosis

Question 6

What causes the accumulation of proteins?

Answer 6

1. Excessive synthesis
2. Defect in cellular transport
   -eg: lots of immunologic in plasma cell