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Anatomical pathology > ENVIRONMENTAL DISEASES > Flashcards

ENVIRONMENTAL DISEASES Flashcards

1
Q

Define Environmental disease?

A

Slide 2

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2
Q

List host factors causes? [4]

A

Slide 2

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3
Q

The effect of climate change on health depends on?

A

Slide 3

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4
Q

Negative effects of climate change may lead to health diseases such as? [4]

A

Slide 4

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5
Q

What is the type of environmental pollution discussed? And it is divided into?

A

Slide 5

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6
Q

Outdoor air pollutants location? [2]

A

Slide 6

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7
Q

With outdoor pollutants which six pollutants are monitored? [6] And which organ will be affected? [1]

A

Slide 6

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8
Q

Indoor air pollutants location? And give 5 common insults or causes?

A

Slide 7

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9
Q

Name four metals associated with harmful effects in humans? [4]

A

Slide 8

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10
Q

Harvard for children because absorb_____________ of lead from food

A

Slide 9
1. 50%

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11
Q

Most absorb lead is taken by___________?
Competes with ______&_______ with a half life of_____?

A
  1. Bone and developing teeth
  2. Calcium &phosphate half life of 20-30 days
    Slide 9
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12
Q

Chronic lead exposure favors the formation of?

A
  1. Cheilitis, fissures, epithelium desquamation, ulcers of the lips, tongue, palate and oral mucosa
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13
Q

Sources of mercury? [3]

A
  1. Diet (fish)
  2. Dental materials (amalgam)
  3. Gold mining
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14
Q

Three forms of mercury?

A
  1. Organic
  2. Inorganic
  3. Metallic
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15
Q

Name two toxic effects of mercury?

A
  1. CNS and Renal damage
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16
Q

List 8 symptoms of mercury toxicity?

A

Slide 12

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17
Q

What is the most common cause of exogenous human cancer?

A

Tobacco

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18
Q

Tobacco prevalent results in?

A
  1. CVS diseases
  2. Chronic respiratory problems
  3. Cancers
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19
Q

Mucosa effects of smoking?

A

Slide 16

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20
Q

List the common lesions assocwith tobacco use?

A

Slide 16
1. Smokers melanomas
2. Oral cancer
3. PD
4. GR/TA
5. Blackh hairy tongue
Nicotine stomatisis

21
Q

Detrimental effects of smoking

22
Q

What are some of the effects of maternal smoking?

23
Q

Passive smoking cause what in children?

A
  1. Increase the risk of respiratory diseases and asthma
  2. May also cause MI, Lung CA and Artherosclerosis
    Slide 21
24
Q

Define Pneumoconiosis?

25
Q

Pmeumoconiosis results from exposure from?

26
Q

Pneumoconiosis development depends on? [4]

A

Slide 23
1. Amount of dust
2. Size and shape of the particle
3. Particles solubility
4. Additional effects of other irritants

27
Q

Pathogenesis of Pneumoconiosis

28
Q

Define Coal worker’s pneumoconiosis?

29
Q

Effects of carbon dust?

A

From asymptomatic anthracisis&raquo_space;»simple CWP&raquo_space;»> complicated CWP or Progressive massive fibrosis
Compromised lung function
Increased susceptibility to tb,bronchitis and emphysema

30
Q

Definitions os Silicosis? And diseases it caused? [4]

31
Q

Pathogenesis of Silicosis

32
Q

Clinical feature of Silicosis?

A
  1. Asymptomatic but dx on radiographs
33
Q

Define Asbestosis?

34
Q

What magnifies Asbestosis?

A

Slide 34
Smoking

35
Q

List 5 diseases related to Asbestosis?

A

Slide 34
1. Pleural effusion, pleural plaque, mesotjioloma, Carcinoma of lungs , Caplan’ s syndrome & Asbestosis

36
Q

Pathogenesis of Asbestosis?

37
Q

List individuals at risk of getting Asbestosis?

38
Q

Symptoms of Asbestosis?

39
Q

Define Drug abuse?

40
Q

Facts about Alcohol?

41
Q

Metabolism of ethanol?

42
Q

What is the legal definition for drunk driving blood alcohol Concerntration?

43
Q

At which concentration does drowsiness and stupor occur respectively?

A
  1. 200ml/dL and 300mg/dL
44
Q

Chronic alcoholics can tolerate greater volume of alcohol due to?

A
  1. Hepatic CYP induction
45
Q

10% of absorbed alcohol is excreted by?

A
  1. Urine
  2. Sweat
  3. Breath
46
Q

Ethanol is metabolized to____________ in hepaticytes by__________

A
  1. Acetaldehyde
  2. Cytosolic ADH (alcohol dehydrogenase)
47
Q

Hepatic acetaldehyde dehydrogenase then converts acetaldehyde to…………… in ………….?

A
  1. Acetate
  2. Mitochondria
48
Q

What are the acute effects ts of alcoholism?

49
Q

What are the chroniceffects of alcoholism?

Anatomical pathology (9 decks)

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