Intoxicación por acetaminofén Flashcards

1
Q

antídoto

A

N- acetilcisteína

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2
Q

organo mas afectado

A

higado

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3
Q

dosis toxica

A

150 mg/ kg

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4
Q

forma de administrar el antídoto

A

oral:
- bolo inicial de 140 mg/ kg
- 70 mg cada 4 horas X 36 horas

intravenoso:
- 150mg/ kg en 200 cc DAD 5% por una hora
-Por 4 horas 50 mg/ kg en 500 cc DAD 5%
- Por 16 horas 100 mg/kg en 1000 cc DAD 5%

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5
Q

cual es el metabolito toxico

A

NAPQI

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6
Q
  • Vida media de eliminación
A

2-2.5 horas

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7
Q

Clinica

A

fase 1: síntomas gastrointestinales
fase 2: asintomático
fase 3: daño hepático
fase 4: recuperación hepática

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8
Q

cuando se usa el carbón activado

A

cuando la ingesta es inferior a 2 horas

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