Intercalated discs connect cardiac muscle fibers into a functional syncytium Flashcards

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1
Q

describe cardiac muscle cells

A
striated
short
fat
branched
interconnected
use sliding filament mechanism
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2
Q

describe cardiac muscles in term of nucleus

A

contains one or at most two large, pale, centrally located nuclei

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3
Q

In contrast, the plasma membranes
of adjacent cardiac cells interlock like the ribs of two sheets of
corrugated cardboard at dark-staining junctions called

A

intercalated discs

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4
Q

Intercalated discs contain anchoring________ and__________

A

desmosomes

gap junctions

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5
Q

The ______ prevent adjacent cells from separating during contraction, and the _____ allow ions to pass from cell to cell transmitting current across the entire heart

A

desmosomes

gap junctions

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6
Q

Because gap junctions electrically couple cardiac cells, the myocardium behaves as a single coordinated unit, or

A

functional syncytium

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7
Q

why is it significant that cardiac cells have 25% to 35% mitochondria in comparison to skeletal muscle having 2%

A

it makes them highly resistant to fatigue which is important because the heart is working all the time and if stops you are dead :(

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8
Q

in contrast to skeletal muscle, the myofibrils of cardiac muscle cells vary greatly in ____ and _____ extensively, accommodating the abundant ______between them.

A

diameter
branch
mitochondria

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9
Q

The system for delivering Ca2+ is ____ elaborate in cardiac muscle cells. The cardiac sarcoplasrnic reticulum is ____ and ____ the large terminal cisterns seen in skeletal muscle. As a result, cardiac muscle fibers do not have ____. In addition, the
T tubules are ____ and ____ than in skeletal muscle.

A
less
simpler
lacks
triads
wider
fewer
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10
Q

Some cardiac muscle cells are ____ excitable

A

self

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11
Q

what are the 2 kinds of myocytes in the heart

A

contractile cardiac muscle cells

pacemaker cells

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12
Q

responsible for the heart’s pumping

activity

A

contractile cardiac muscle cells

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13
Q

certain locations in the heart contain special noncontractile cells, called ____ cells, that spontaneously depolarize.

A

pacemaker

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14
Q

what is the special property of the heart called in terms of self excitability

A

automaticity

autorhythmicity

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15
Q
Because heart cells are electrically
joined together by gap junctions, these
cells can initiate not only their own
\_\_\_\_\_-, but also that of the rest
of the \_\_\_\_
A

depolarization

heart

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16
Q

if you cut all of the nerves of the heart will it still beat

A

yes, because it requires no neutral input

17
Q

the heart contracts as a ____

A

unit

18
Q

all fibers in the heart contract as a ____ or the heart ________

A

unit

doesn’t contract at all

19
Q

recruitment cannot happen in the heart

because it acts as a

A

single huge motor unit.

20
Q

The influx of Ca2+ from extracellular fluid triggers

A

Ca2+

release from the SR

21
Q

In cardiac muscle, depolarization opens _________ in the plasma membrane. These _______ Ca2+ channels allow entry of 10-20% of the Ca2+ needed for contraction. Once inside, this influx of
Ca2+ triggers Ca2+ -_____channels in the SR to release bursts of Ca2+ (“calcium sparks”) that account for the other _______ of the Ca2+ needed for contraction

A

special Ca2+ channels
slow
sensitive
80-90%

22
Q

Tetanic contractions ______ occur in cardiac muscles

A

cannot

23
Q

If the heart were to contract tetanically, it would be ___________-, and so would be _____ as a pump

A

unable to relax and fill

useless

24
Q

The absolute refractory period in the heart is nearly ______________, which prevents ________ contractions.

A

as long as the contraction itself

tetanic

25
Q

which type of respiration does the heart depend on

A

aerobic

26
Q

Consequently, the real danger of an inadequate blood supply to the myocardium is not
lack of nutrients, but lack of

A

oxygen