Interactive Cases in General Internal Medicine 1 NEWLY added Flashcards
60 yr old man
Chest pain
Tight, 4 hrs
Nausea
Sweating
Breathlessness
HTN
DH: amlodipine
What is the diagnosis?
A. Pneumonia
B. Pericarditis
C. Myocardial infarction
D. Aortic dissection
E. Costochondritis
C. Myocardial infarction
If someone presents with chest pain (you think is of cardiac origin) what are the investigations you would want to do
- ECG
- Troponin
- +ve: coronary angiography
- -ve: ETT
- Echocardiography
How soon should you do a troponin?
6 hours after they started having pain
What are the differentials of chest pain?
Cardiac:
- IHD: Stable & unstable angina, STEMI, NSTEMI
- Aortic disseaction
- Pericarididtis
Resopiratory
- PE
- Pneumonia
- Pneumothorax
GI
- Oesophageal spasm
- Oesophagitis, Gastritis
Muscluloskeletal
- Costochondritis
What are differentiating feature of chest pain of cardiac origin
IHD: jaw, radiating down the arm
pericarditis: worse on inspiration, better on leaning forward
Aortic dissection: tearing, along the back, difference between the blood pressure in both arms
What are differentiating feature of chest pain of repiratory origin
PE:
Pneumonia:
Pneumothorax:
Patient has had mwlanoma metastaiszed to th brain and now on high dexamethasone.
Complains now of chest pain.
What is the chest pain due to
steriod: immunosupression - infection
oesophagitis - fungal infection
History:
60 yr old man • Chest pain • tight, 2 hrs • nausea & sweating • PMH: HTN • DH: amlodipine
Examination:
Temp: 37.0oC • HS: S1 + S2 • BP: 120/80 (L), 118/75 (R) • Chest: clear • Abdomen is soft, nontender
What is the most appropriate investigation?
A. CK
B. CXR
C. ECG
D. Echocardiogram
E. Troponin
C. ECG
feature of viral pericarditis
fever, sweating
better when leaning forward
pleuritic chest pain
What does this ECG show?
What should happen to this patient?
anteriorlateral MI
Should be sent inmmidiatly to a cathlab for percutaneus coronary intervention
What does this ECG show?
inferior STEMI
2, 3, AVF
What are teh ECG changes and artery affected in an:
- anterior MI
- Lateral MI
- Inferior MI
anterior MI:
- LAD
- V1-V4
Lateral MI:
- Circumflex
- V5, V6, I, aVL
Inferior MI:
- RCA
- II, III, aVF
what are the cardiac enzymes
When do you measure troponin and when does it rise and when does it fall
troponin goes up within 6-121 hour
but is up for several days (3-4)
History:
30 year old man • Collapse • HPC: – Before: no warning – During: no tongue biting – After: not confused • FH: brother died at a young age
Examination:
• HS: S1 + S2 + 0 • BP: 120/80 (lying), 115/75 (standing) • Vesicular breath sounds • Abdomen: soft, non-tender • CN I-XII: NAD, Normal I, T, P, R, C, S, G
What is the most likely cause of his collapse?
A. Aortic stenosis
B. Pulmonary embolism
C. Postural hypotension
D. Seizure
E. Tachyarrhythmia
E. Tachyarrhythmia
EXLUSION: says normal sounds (no ejection systolic murmur)
no drop in blood pressure when standing(not postural hypotension)
no post ictal period, no tongue biting (no seizure)
no risk factors for PE, or breathlessness (no PE)
What do you look out for in a person that collapsed?
What are differentiating symptoms?
Cardiac: no warning, sudden
Seizure: tongue biting, confused afterwards (post ictal period)
Vasovagal: feel dizzy come around quickly and
What are differentials of collapse?
Hypoglycaemia:
cardiac:
- vasovagal
- ouflow obstruction: PE, HOCM, aortic stenosis
- postural hypotension
neurological:
- seizure
What are the investigations you would do for the different causes of collpase
Arrhythmias –
- Tachycardia, bradycardia
DO an ECG (? Long QT), cardiac monitor, 24 hour tape
Outflow obstruction
- Left: Aortic stenosis, HOCM
- Right: PE
Do a Low volume/slow rising pulse, ESM, Echocardiogram
Postural hypotension
Lying/standing BP
What is a long QT syndrome?
- Abnormal ventricular repolarization
- Congenital e.g. mutations in K+ channels
- FH of sudden death
- Acquired: low K+ / Mg2+ , drugs
History:
• 45 year old man • Fever • Malaise • IV drug use
Examination:
Temp: 38oC • raised JVP to earlobes • HS: S1 + S2 + PSM (louder on inspiration) • Hepatomegaly
What is the cause of his raised JVP?
A. Constrictive pericarditis
B. Congestive cardiac failure
C. Aortic regurgitation
D. Mitral regurgitation
E.Tricuspid regurgitation
Tricuspid regurgitation
Which murmurs are heard louder on inspiration and expiration?
Left - expiration
right- inspiration
What are differentials of a raised JVP
-
R heart failure:
- Secondary to L heart failure (CCF)
- Pulmonary HTN (PE, COPD etc.)
-
Tricuspid regurgitation:
- Valve leaflets
- R ventricle dilatation
-
Constrictive pericarditis:
- Infection e.g. TB
- Inflammation: CTD
- Malignancy
What give you a pan systolic murmur?
tricuspid regurgitation
mitral regurgitation
Differentiate if louder on inspiration or experiation
What are all the systolic murmurs?
Aortic stenosis
Mitral regurgitation
Tricuspid regurgitation
VSD
how do you differentiate an aortic stenosis from an mitral regurgutation?
Where is it the loudest?
Mitral regurgitation: loudest at the left 5th intercostal space mid clavicular line and radiates to the axilla
Aortic stenosis: louddest at the right 2nd intercostal space radiates to the carotids
What are assosiated feature?
aortic stenosis: slow rising pulse
mitral regurgitation: displaced apex beat
VSD: young and no other features
History:
65 year old man • Breathlessness • Palpitations • PMH: HTN • DH: Bendroflumethiazide
Examination
Temp: 38oC • PR: 160, irregular • BP: 110/80 mmHg • Dull percussion note & coarse crackles L base
What would you expect to see on his ECG?
A. Atrial fibrillation
B. Sinus tachycardia
C. SVT
D. VF
E. VT
AF
What are the different types of tachycardias/ palpitations?
What are the differential for those
Sinus tachycardia:
Sepsis, hypovolaemia, endocrine (thyrotoxicosis, phaeochromocytoma)
SVT
Re-entry circuit
Atrial fibrillation
Thyrotoxicosis, ischaemia, chest infection, alcohol
VT
ischaemia, electrolyte abnormality, long QT
What does this ECG show?
What could have caused this?
Sinus tachycardia (p wave before every QRS)
Causes:
- Sepsis
- hypovolaemia
- endocrine (thyrotoxicosis, phaeochromocytoma)
What does this ECG show?
What are the causes of it?
SVT
re entry circuit
What are the 2 different types of SVT?
When do you see the delta wave and when do you see tachycardia?
delta wave: when it is going down (from atria down into the ventricles) the accessory pathyway but you won#t have tachycarida
tachycardia: when the electrical impulse comes back up the accessory pathway into the atria
What is an ECG that is regular, no p wave and tachycardia
SVT
What does this ECG show?
What causes it?
AF
causes
Thyrotoxicosis, alcohol
Heart: muscle, valve, pericardium
Lungs: Pneumonia, PE, cancer
What does this ECg show?
atrial flutter
What does this ECG show?
What are the causes for it
Ventricular tachycardia
causes:
- Ischaemia
- electrolyte abnormality
- long QT
What is the management of SVT?
vagal maneuvers
Adenosine (cardiac monitor)
DC cardiovesion if evidence of haemodynamic compromise
What is the management of AF
Rhythm control
- If onset > 48hours, anticoagulate for 3-4 weeks before cardioversion
Rate control
- beta blocker
- Digoxin
Think of the underlying Cause
Think of the Complications (Anticoagluation)
What is the management of VT?
If no haemodynamic compromise: IV Amiodarone
Look for & treat underlying cause
ICD
Pulseless VT: defibrillate
What does this ECG show?
HYPERTENSION
LVH by voltage criteria
(Remember SR)
Deep S in V1/2
Tall R in V5/6
S in V1 + R in V5 or V6 (whichever is larger) ≥ 7 large squares
What drug used to treat AF does not work in infections?
digoxin
What is the difference between cardioversion and defibrillation
defibrillation: you don’t sync it with the rhythm you just shock
What does this ECG show?
1 st degree heart block
What does this ECG show
2nd degree heart block
p wave no QRS
What does this ECG show
3rd degree heart block
What are the ECG’s that can be seen in the following conditions?
- Ischaemia
- Arrhythmia or conduction defects
- Ventricular strain or hypertrophy
Ischaemia
ST, T, Q
Arrhythmia or conduction defects
Rate, Rhythm
PR, QRS, QT
Ventricular strain or hypertrophy
Axis, R, S
What would a tall R wave in V1 indicate
right heart side strain - PE
history:
65 year old woman • Breathlessness • Onset: over a few hours • Orthopnoea • PMHx: 2 X MIs • DH: aspirin, simvastatin, ramipril, bisprolol
Examination:
Temp : 36.5oC • raised JVP • HS: S1 + S2 + S3 • Chest: fine crackles • Peripheral oedema
What is the 3rd heart sound due?
A. Is due to closure of mitral valve
B. Is due to closure of aortic valve
C. Is due to an atrial septal defect
D. Is associated with ventricular hypertrophy
E. Is associated with ventricular filling
E. Is associated with ventricular filling
What are the heart sounds associated with?
Closure of mitral valve B - S 1
Closure of aortic valve C - S 2
Atrial septal defect - Fixed wide splitting of S2
Associated with ventricular filling - S3
Associated with ventricular hypertrophy - S4
What is the Management of this patient?
Management of acute heart failure
- Sit up
- Oxygen
- Furosemide (IV)
- GTN infusion)
- Treat the underlying cause
CASE:
History:
78 year old man • Brought in by ambulance • Unconscious • Not breathing • Carotid pulse is absent • Temp 29oC
What does the ECG show?
A. Asystole
B. AF
C. VF
D. VT
E. SVT
VF
CASE:
History:
78 year old man • Brought in by ambulance • Unconscious • Not breathing • Carotid pulse is absent • Temp 29oC
How would you manage this patient?
HE is cold don’t administer any drugs until he is warmed up
How do manage VF/ pulseless VT
- Shock
- CPR (2 min)
- Assess rhythm
- Adrenaline every 3-5 min
- Amiodarone after 3 shocks
- Correct reversible causes
how do you manage someone with Asystole
CPR (2 min)
Adrenaline every 3-5 min
Correct reversible causes
30 yr old woman • URTI • Pleuritic chest pain • Better when leaning forward
What is the diagnosis?
pericarditis
What are the reversible causes of pulseless VT
4H: Hypovolaemia, Hypothermia, hypokalaemia, Hypoxia
4T: Tamoponade, Tension pneumothorax, Toxins, Thrombosis
Do you shock a patient in asystole?
NO
just give adrenaline
What are the differentials for pleuritic chest pain
5 P’s
PE
Pericarditis
Pneumonia
Pleural patholofy
Sub diaphragmatic pathology