Interactions

Question 1

Colchicine and Statins

Answer 1

Best to avoid because it can increase the risk of rhabdomyolysis eg breakdown of muscle tissue = pain

Question 2

Probenecid and methotrexate

Answer 2

Be mindfull that Probenecid can keep methotrexate in he body for longer thus increases toxicity risk

Question 3

Allopurinol and what other immunosuppressant?

Answer 3

Azathioprine and mercaptopurine

-these drugs are generally used in organ transplant - thus any concentration decrease may cause the organ to be REJECTED - very bad news