Integumentary System Flashcards
Structures that are part of the integument.
- Skin.
- Hair.
- Nails.
- Glands.
- protects against U V light, microorganisms, water loss.
Protection
- sensory receptors for heat, cold, touch, pressure, pain.
Sensation
- modulation of blood flow through the skin and activity of sweat glands.
Temperature regulation
from a molecule made in the skin when exposed to UV light.
Vitamin D production
- small amounts of waste products eliminated.
Excretion
- Superficial layer of stratified squamous epithelial tissue.
- Protection and reduces water loss.
Epidermis
- Deep layer of connective tissue.
- Structural strength.
Dermis
- Not part of skin.
- Loose connective tissue that connects skin to underlying structures.
Subcutaneous tissue.
- Avascular; nourished by diffusion from capillaries of the papillary layer of the dermis.
- Composed of epithelial cells arranged into layers or strata.
- Separated from dermis by basement membrane.
Epidermis
- most cells.
- Produce keratin for strength.
Keratinocytes
- contribute to skin color. Melanin produced by these cells then transferred to keratinocytes.
- Same number of melanocytes in all people.
Melanocytes
- part of the immune system.
Langerhans cells
*detect light touch and superficial pressure.
Merkel cells
- as cells move outward through the layers they fill with keratin, die, and serve as a layer that resists abrasion and forms permeability layer.
Keratinization
- Deepest portion of epidermis and single layer of cuboidal or columnar cells.
- High mitotic activity; keratinocyte stem cells undergo mitosis about every 19 days;
- one daughter cell remains in the stratum basale to divide again, while the other daughter cell is pushed to the surface and becomes keratinized.
- Desmosomes hold the keratinocytes together and provide structural strength.
- It takes 40 to 56 days to move from the stratum basale to the surface and be sloughed off.
Stratum basale (germinativum)
- Eight to ten layers of many-sided cells that flatten as they are pushed upward.
- Contain new desmosomes, lipid-filled lamellar bodies, and additional keratin fibers.
Stratum spinosum
- Two to five layers of flattened, diamond-shaped cells.
- Contains protein granules of keratohyalin that accumulate in the cytoplasm.
- Lamellar bodises move to the plasma membrane and release their lipid contents into the extracellular space.
- In superficial layers, nucleus and other organelles degenerate and cell dies; the keratin fibers and keratohyalin granules do not degenerate.
Stratum granulosum
- Thin, clear zone of dead keratinocytes with indistinct boundaries.
- Found only in palms and soles.
Stratum lucidum
- Most superficial and consists of 25 or more layers of dead, overlapping squamous cells joined by desmosomes called cornified cells.
- Cell remnants have a soft protein envelop of keratin, a mixture of keratin fibers and keratohyalin.
Stratum corneum
- this (designation refers only to the epidermis)
- Has all 5 epithelial strata.
- Found in areas subject to pressure or friction.
- Palms of hands, fingertips, soles of feet.
- Fingerprints and footprints.
- Papillae of underlying dermis in parallel rows.
Thick Skin
- Composed of 4 strata (no stratum lucidum).
- More flexible than thick skin.
- Covers rest of body.
- Hair grows here.
Thin skin
Increase in number of layers in stratum corneum. When this occurs over a bony prominence, a corn forms.
Callus
- Determined by 3 factors: pigments in the skin, blood circulating through the skin
Skin Color
provides for protection against UV light. Group of chemicals derived from amino acid tyrosine. Colored brown to black, may be yellowish or reddish
Melanin
processes extend between keratinocytes; deposit melanosomes (vesicles that contain melanin)
Melanocytes
deficiency or absence of pigment; production determined by genetics, hormones, exposure to light.
Albinism