Chapter 4 Flashcards
Tissue classification based on structure of cells, composition of noncellular, — and cell function.
extracellular matrix
microscopic study of tissues.
Histology
removal of tissues for diagnostic purposes
Biopsy
examination of organs of a dead body to determine cause of death.
Autopsy
form early in embryonic development and give rise to all tissues of the body.
Embryonic germ layers
• Inner layer
• Forms lining of digestive tract and derivatives
Endoderm
• Middle layer
• Forms tissues as such muscle, bone, blood vessels
Mesoderm
• Outer layer
• Forms skin and neuroectoderm (which forms nervous system; neural crest cells give rise to peripheral nerves, skin pigment cells, medulla of the adrenal gland, and face tissues.)
Ectoderm
• Mostly composed of cells; very little extracellular matrix
• Covers body surfaces and forms glands.
epithelial tissue
connects the basal layer to underlying tissue
Basement membrane
materials must move by diffusion from underlying connective tissue
Avascular
Consists of two layers - basal lamina and reticular lamina
Basement Membrane
Consists of two layers - basal lamina and reticular lamina
Basement Membrane
consists of lamina lucida and lamina densa
Basal lamina
one layer of cells. Each extends from basement membrane to the free surface.
Simple
more than one layer. Shape of cells of the apical layer used to name the tissue.
Stratified
tissue appears to be stratified, but all cells contact basement membrane, so it is in fact simple.
Pseudostratified columnar
special type of stratified epithelium where the cell shape changes from cuboidal/columnar to squamous-like when stretched.
Transitional
flat, scalelike.
Squamous
about equal in height and width.
Cuboidal
taller than wide.
Columnar
Free surfaces of epithelium.
Free Surface Modifications
reduce friction; called endothelium
Smooth
in transitional epithelium where organ must be able to change shape; urinary bladder.
Folds
increase surface area for absorption or secretion.
Microvilli
are modified as sensory receptors; stereocilia of the inner ear (not cilia).
Specialized microvilli
move mucus across the surface of cells.
Cilia
Cell Connections
Found on lateral and basal surfaces of cells.
disk-shaped regions of cell membrane; often found in areas that are subjected to stress.
• Consists of an especially adhesive material between the cells and intermediate protein filaments that extend into cytoplasm of cells.
• Stratified squamous epithelium of the skin.
Desmosomes
half of a desmosome; attach epithelial cells to basement membrane preventing movement of the tissue.
Hemidesmosomes
hold cells together, form permeability barrier.
Tight Junctions
found just below tight junctions that help anchor epithelial cells to each other to prevent passage of materials between cells; provides additional strength to the tight junctions.
Adhesion belts
protein channels aid intercellular communication.
• Allows ions and small molecules to pass through.
• Function in epithelium is unclear.
Gap Junctions
protein channels aid intercellular communication.
• Allows ions and small molecules to pass through.
• Function in epithelium is unclear.
Gap Junctions
Specialized secretory organs of epithelium with supporting network of С.Т.
Glands
no open contact with exterior; no ducts; have an extensive network of blood vessels; produce hormones.
Endocrine
open contact maintained with exterior by way ducts that open onto the free surface of the epithelium.
Exocrine
• Multicellular glands with a single, nonbranched duct.
• Secretory portion can be tubular or acinar (sac-like)
• Includes simple tubular, simple branched tubular, simple acinar, and simple branched acinar
Simple glands
• Multicellular glands with ducts with many branches.
• Secretory portion may be tubular, acinar or both.
• Includes compound tubular, compound acinar, and compound tubuloacinar.
Compound glands
exocytosis (most common type).
Merocrine
pinched off fragments of gland cells; mammary glands and ceruminous glands.
Apocrine
shedding of entire cells; sebaceous glands.
Holocrine
Abundant; found in every organ.
Connective Tissue
Specialized cells produce the extracellular matrix. Descriptive word stems.
Cells of Connective Tissue
create the matrix.
Blasts
maintain the matrix.
Cytes