Integumentary (skin) Flashcards
What makes up the skin
Skin
Nails
Hair
Sweat glands
Oil glands
I bag percentage of body mass is the skin?
10-16%
Skin thickness of the eye lids? In mm
0.5mm
What has the thickness of 1-2 cm
Heel/ball of foot
1) Which skin layer consists of a single row of keratinocytes? & what else happens on this layer
Stratum basale
&
Cell division happens here
2) How many layers does the stratum spinosum consist of? And of what?
Hint: there’s 3 things
8-10 layers
Keratinocytes
Langerhans
Melanocytes
What layer of skin consists of flattened, keratinocytes?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum granulosum
The stratum granulosum has certain granules present here what are they?
Lamellar granules
Which layer of the skin is keratin produced ?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum Granulosum
Stratum lucindum skin layer is present only where? & how many layers of keratinocytes does this layer have
Palms, finger tips and soles of feet!
3-5 layers of flattened and dead keratinocytes
The stratum lucindum layer of skin has 3-5 layers of flat & dead keratinocytes that contain large amounts of what?
Keratin and thickened plasma membranes
How many layers does the stratum corneum have? & what do the lipids from the lamellar granules do?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
25 - 30 layers of DEAD keratinocytes .
- Create a water repellant barrier
What is the manufacturing layer that holds everything together !!
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum basale
What is the last living skin layer ?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum granulosum
What is it called when cells die and what layer does this happen?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Apoptosis & stratum granulosum
Which layer has the chief function of waterproofing ?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum Granulosum
Which layer of skin is responsible of stretching ?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum lucindum
Which layer of skin has contains proteins responsible for for apoptosis
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum lucindum
Which layer protects inner layers from mechanical damage ?
Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum
Stratum corneum
What does keratin do to the skin?
Makes it stronger and flexible
Which layer does not have blood vessels?
Hint: Dermis
Epidermis
2 layers mainly the skin is made of ?
Reticular layer
Papillary layer
Which layer contains epidermal ridge and dermal papilla?
Papillary layer
Which layer of skin are These present on?
Arrector pilli muscle
Sebaceous (oil) gland
Sweat gland
Mecocrine sweat gland
Papillary layer or reticular layer
Reticular layer
5 functions of the skin !??
Serves as blood supply
Sensitivity
Thermoregulation
Immunity
Excretion
Endocrine
Protection
Layers of skin form the top to bottom ?
Stratum corneum
Stratum lucindum
Stratum granulosum
Stratum spinosum
Stratum basale
Basement membrane
What do sebaceous gland secrete?
Oily substance known as sebum
What does that secretion from the sebaceous gland contain ?
Lactic acid
What does lactic acid do to the PH of h the skin ?
Lowers it PH
Where is glyolipid produced ??
Stratum Granulosum, lucindum & corneum
Why is glycolipids produced in those layers ??
Prevents pathogens 🦠 migrating through as it cements the layers together !!
When do you loose heat from the body
Vasoconstriction or dilation
Vasodilation
What’ does the body do to cool its self down?
Sweating !!
What these different types of?
Meissners corpuscle
Pacinian corpuscle
Merkels discs
Ruffinis corpuscle
Receptors
Ruffinis corpuscle is responsible for ?…
Temperature
Merkels discs detect what ? & found where?
Fingertips
Detect static pressure & touch
Pacinian corpuscle detects …
grosss pressure changes
& vibration - found deeper in skin
What does the meissners corpuscle detect?
Light touch and dynamic pressure
MLS of water that evaporates from the skin?
400mls
Skin has a network of blood vessels that hold what percentage of total blood flow in resting adult
8-10%
What vitamin Dioes our body create from direct ☀️ light?
Vitamin D
What is osteomalacia ?
Bending of bones/Ricketts.
What 3 things give us skin colour 😋?
Haemaglobin
Melonin
Carotine
Beta carotene - vivid yellow orange, red colour to foods
The body converts beta carotene into vitamin _____ & plays critical role in cell growth, and maintains healthy organs
A
What does glabrous mean?
Smooth skin: no hair
How does our body create vit D
Direct sunlight
What does vit D allow your body to do?
Absorb calcium
What does ostea malacia mean (not rickets)
Bone softening
Well oxygenated blood has how many oxygen units attached to the heamaglobin?
4
The less oxygen that’s attached to haemaglobin how will the blood look?
Darker (cyanosis)
What vitamin is beta carotene converted to?
Vit A
Whre is carotene stored ?
Stratum corneum
& Fatty layers
What is the lunule?
White part of nail near nail bedq
What happens if the nail matrix or nail bed is damaged ?
It can prevent future growth and nail growing properly
What is the eponychium on the nail?
Cuticle
MUST KNOW!
What are the types of melanin
Eumelanin
& Phomelanin
What cells make melanin ?
What layer are these cells in?
Melanocytes
Basal epidermis
In this layer where the melanocytes are present what is the ratio of melanin to keratinocytes
1:10
1 - melanocytes
10 - Keratinocytes
Phomelanin what colour skin is it incharge of?
Yellow to red
What colours eumelanin responsible for ?
Dark brown to black
MUST KNOW: HAIR
What secures hair ? Not roots btw
Dermal papilla
How do we end up becoming grey?
Melanocytes become more ineffective
Revision: melanocytes create a pool of melanin that is spread OUT!!
Melanocytes are becoming less effective what’s the repercussion?
Greying of hair