Integumentary (skin) Flashcards

1
Q

What makes up the skin

A

Skin
Nails
Hair
Sweat glands
Oil glands

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2
Q

I bag percentage of body mass is the skin?

A

10-16%

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3
Q

Skin thickness of the eye lids? In mm

A

0.5mm

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4
Q

What has the thickness of 1-2 cm

A

Heel/ball of foot

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5
Q

1) Which skin layer consists of a single row of keratinocytes? & what else happens on this layer

A

Stratum basale
&
Cell division happens here

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6
Q

2) How many layers does the stratum spinosum consist of? And of what?
Hint: there’s 3 things

A

8-10 layers
Keratinocytes
Langerhans
Melanocytes

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7
Q

What layer of skin consists of flattened, keratinocytes?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum granulosum

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8
Q

The stratum granulosum has certain granules present here what are they?

A

Lamellar granules

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9
Q

Which layer of the skin is keratin produced ?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum Granulosum

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10
Q

Stratum lucindum skin layer is present only where? & how many layers of keratinocytes does this layer have

A

Palms, finger tips and soles of feet!
3-5 layers of flattened and dead keratinocytes

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11
Q

The stratum lucindum layer of skin has 3-5 layers of flat & dead keratinocytes that contain large amounts of what?

A

Keratin and thickened plasma membranes

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12
Q

How many layers does the stratum corneum have? & what do the lipids from the lamellar granules do?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

25 - 30 layers of DEAD keratinocytes .
- Create a water repellant barrier

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13
Q

What is the manufacturing layer that holds everything together !!

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum basale

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14
Q

What is the last living skin layer ?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum granulosum

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15
Q

What is it called when cells die and what layer does this happen?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Apoptosis & stratum granulosum

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16
Q

Which layer has the chief function of waterproofing ?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum Granulosum

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17
Q

Which layer of skin is responsible of stretching ?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum lucindum

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18
Q

Which layer of skin has contains proteins responsible for for apoptosis

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum lucindum

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19
Q

Which layer protects inner layers from mechanical damage ?

Stratum basale
Stratum corneum
Stratum granulosum
Stratum lucindum
Stratum spinosum

A

Stratum corneum

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20
Q

What does keratin do to the skin?

A

Makes it stronger and flexible

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21
Q

Which layer does not have blood vessels?
Hint: Dermis

A

Epidermis

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22
Q

2 layers mainly the skin is made of ?

A

Reticular layer
Papillary layer

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23
Q

Which layer contains epidermal ridge and dermal papilla?

A

Papillary layer

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24
Q

Which layer of skin are These present on?

Arrector pilli muscle
Sebaceous (oil) gland
Sweat gland
Mecocrine sweat gland

Papillary layer or reticular layer

A

Reticular layer

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25
Q

5 functions of the skin !??

A

Serves as blood supply
Sensitivity
Thermoregulation
Immunity
Excretion
Endocrine
Protection

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26
Q

Layers of skin form the top to bottom ?

A

Stratum corneum
Stratum lucindum
Stratum granulosum
Stratum spinosum
Stratum basale
Basement membrane

27
Q

What do sebaceous gland secrete?

A

Oily substance known as sebum

28
Q

What does that secretion from the sebaceous gland contain ?

A

Lactic acid

29
Q

What does lactic acid do to the PH of h the skin ?

A

Lowers it PH

30
Q

Where is glyolipid produced ??

A

Stratum Granulosum, lucindum & corneum

31
Q

Why is glycolipids produced in those layers ??

A

Prevents pathogens 🦠 migrating through as it cements the layers together !!

32
Q

When do you loose heat from the body
Vasoconstriction or dilation

A

Vasodilation

33
Q

What’ does the body do to cool its self down?

A

Sweating !!

34
Q

What these different types of?
Meissners corpuscle
Pacinian corpuscle
Merkels discs
Ruffinis corpuscle

A

Receptors

35
Q

Ruffinis corpuscle is responsible for ?…

A

Temperature

36
Q

Merkels discs detect what ? & found where?

A

Fingertips

Detect static pressure & touch

37
Q

Pacinian corpuscle detects …

A

grosss pressure changes
& vibration - found deeper in skin

38
Q

What does the meissners corpuscle detect?

A

Light touch and dynamic pressure

39
Q

MLS of water that evaporates from the skin?

A

400mls

40
Q

Skin has a network of blood vessels that hold what percentage of total blood flow in resting adult

A

8-10%

41
Q

What vitamin Dioes our body create from direct ☀️ light?

A

Vitamin D

42
Q

What is osteomalacia ?

A

Bending of bones/Ricketts.

43
Q

What 3 things give us skin colour 😋?

A

Haemaglobin
Melonin
Carotine

44
Q

Beta carotene - vivid yellow orange, red colour to foods
The body converts beta carotene into vitamin _____ & plays critical role in cell growth, and maintains healthy organs

A

A

45
Q

What does glabrous mean?

A

Smooth skin: no hair

46
Q

How does our body create vit D

A

Direct sunlight

47
Q

What does vit D allow your body to do?

A

Absorb calcium

48
Q

What does ostea malacia mean (not rickets)

A

Bone softening

49
Q

Well oxygenated blood has how many oxygen units attached to the heamaglobin?

A

4

50
Q

The less oxygen that’s attached to haemaglobin how will the blood look?

A

Darker (cyanosis)

51
Q

What vitamin is beta carotene converted to?

A

Vit A

52
Q

Whre is carotene stored ?

A

Stratum corneum
& Fatty layers

53
Q

What is the lunule?

A

White part of nail near nail bedq

54
Q

What happens if the nail matrix or nail bed is damaged ?

A

It can prevent future growth and nail growing properly

55
Q

What is the eponychium on the nail?

A

Cuticle

56
Q

MUST KNOW!
What are the types of melanin

A

Eumelanin
& Phomelanin

57
Q

What cells make melanin ?
What layer are these cells in?

A

Melanocytes
Basal epidermis

58
Q

In this layer where the melanocytes are present what is the ratio of melanin to keratinocytes

A

1:10
1 - melanocytes
10 - Keratinocytes

59
Q

Phomelanin what colour skin is it incharge of?

A

Yellow to red

60
Q

What colours eumelanin responsible for ?

A

Dark brown to black

61
Q

MUST KNOW: HAIR

What secures hair ? Not roots btw

A

Dermal papilla

62
Q

How do we end up becoming grey?

A

Melanocytes become more ineffective

63
Q

Revision: melanocytes create a pool of melanin that is spread OUT!!

A
64
Q

Melanocytes are becoming less effective what’s the repercussion?

A

Greying of hair