Integumentary Flashcards
What is the appearance of basal cell carcinoma?
Slow-growing
Dome shaped
Shiny/translucent/pearly
Malignant melanoma assessment
Description and comprehensive skin history reveal sun exposure and change of the lesion’s appearance in its symmetry, diameter, color, or border.
Melanoma ABCDE rules:
A: Asymmetry
B: Irregular border
C: Variable color
D: Diameter
E: Evolving
The general skin examination shows evidence of sun exposure.
Squamous cell carcinoma
Presents as red, scaly, slightly elevated lesions with irregular borders.
Lesion often appears on face or lips, or can be an oral lesion inside the mouth or on the tongue. Sun-exposed areas are the most common regions of SCC.
Actinic keratosis
Bulla
large blister (larger than 0.5cm in diameter)
Vitiligo
a series of discolored patches on the skin Appearing suddenly, these patches present as macules of varying sizes with smooth borders. Vitiligo often occurs with hypothyroidism or other autoimmune diseases.
What are the 7 functions of the skin?
Temperature regulation
Barrier Protection
Excretion and Absorption
Vitamin D Production
Immunological Surveillance
Mirror for Internal disease processes
Indicator of General Health
Melasma (chloasma)
commonly occurs during pregnancy and in women who use oral contraceptives
characterized by the appearance of dark macules on the face. More common in brown-skinned women
xerosis
dry skin, rough, scaly, and wrinkled
Eczema (atopic dermatitis)
Infantile form: Vesicle formation, oozing, and crusting with excoriation that begins on the cheeks and spreads to the scalp, arms, trunk, and legs; often disappears by the age of 5
often have family histories of asthma or hay fever
Contact dermatitis
delayed hypersensitivity to materials such as metals, chemicals, drugs, and poison ivy. The condition affects the head, neck, trunk, arms, hands, abdomen, groin, and lower extremities. This allergic skin reaction usually occurs days after the skin contact with the allergen. Emollients and topical anti-inflammatory medication are standard therapy.
Urticaria (hives)
elevated, pink or red, itchy blotches or plaques of varying size
angioedema
swelling of the eyes, face, lips, and mucous membranes
Kaposi’s Sarcoma (KS)
cancer that develops within blood and lymphatic vessels. Tumors appear as purple-colored, painless, irregularly shaped lesions on the skin of the face, trunk, and extremities. These blood vessel tumors can also occur within organs such as the lungs and digestive tract. The underlying cause of KS is infection with human herpesvirus 8 (HHV-8). Immunosuppressed individuals are at increased risk for this disorder, particularly those with HIV infection and those who have had organ transplantation.
Arises from the melanocytes. Differ in size and shape and may arise from dysplastic nevi or new molelike growths. Slightly raised and brown or black in color. Can appear anywhere on the body and may be slowly or rapidly growing.
Malignant Melanoma s/s
Patient presents with a lesion that has changed in size, shape, and appearance.
Lesion is usually asymptomatic, but occasionally pruritus is observed.
Cosmetic concerns about appearance of the lesion are frequent.
Skin cancers may appear suddenly or develop over time.
Malignant Melanoma assessment
Description and comprehensive skin history reveal sun exposure and change of the lesion’s appearance in its symmetry, diameter, color, or border.
Melanoma ABCDE rules:
A: Asymmetry
B: Irregular border
C: Variable color
D: Diameter
E: Evolving
The general skin examination shows evidence of sun exposure.
Malignant Melanoma diagnostics
Biopsy, with assessment of spread of disease if the biopsy is positive.
Malignant Melanoma treatment
Surgery with a wide excision.
Cryosurgery, radiation, and chemotherapy.
Yearly skin checkup by a dermatologist.
Monthly skin self-assessment by patient.
Advice about protection from sun rays.
Basal Cell Carcinoma
Arises from the nonkeratinizing cells of the basal layer of the epidermis. It is nonmetastasizing.