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Cardiovascular 2018 > Integration of Cardiovascular Mechanisms > Flashcards

Integration of Cardiovascular Mechanisms Flashcards

1
Q

What are the three factors affecting SV?

A

Pre-load
Myocardial Contractility
After-load

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2
Q

MAP=

A

CO x SVR
or
DBP + 1/3 Pulse Pressure

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3
Q

CO=

A

HR x SV

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4
Q

What is SVR regulated by?

A

Regulated by vascular smooth muscle

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5
Q

What is the result of vasoconstriction in SVR?

A

Increased SVR and MAP upstream

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6
Q

What is the result of vasodilatation in SVR?

A

Decreased SVR and MAP

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7
Q

What is resistance to blood flow directly proportional to?

A

Blood Viscosity
and
Length of blood vessels

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8
Q

What is resistance to blood flow inversely proportional to?

A

Radius of blood vessels to the power of 4

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9
Q

What is the biggest influence on resistance to blood flow?

A

Radius of blood vessels

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10
Q

What are the factors responsible for extrinsic control of VSM?

A

Nerves and Hormones

Baroreceptor reflex

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11
Q

What are VSM supplied by?
What is the neurotransmitter?
What does it act upon?

A

Sympathetic supply
Noradrenaline
alpha receptors

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12
Q

What is vasomotor tone?

A

partial constriction due to continuous release of noradrenaline at rest

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13
Q

What does the hormone adrenaline act upon?

A

Organ specific

alpha receptors and b receptors

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14
Q

Where are alpha receptors dominant?

A

Skin, gut, kidneys

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15
Q

Where are B receptors dominant?

A

Cardiac muscle and skeletal muscle

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16
Q

What does adrenaline acting on alpha receptors do?

A

cause vasoconstriction

17
Q

What does adrenaline acting on B receptors do?

A

cause vasodilatation

18
Q

What does angiotensin II cause?

A

vasoconstriction

19
Q

What does antidiuretic hormone (vasopressin) cause?

A

vasoconstriction

20
Q

Why must intrinsic control of VSM be possible?

A

To match blood flow to metabolic needs of tissue

Cardiovascular 2018 (39 decks)

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