Embryology of the heart and the great vessels Flashcards
Which germ layer is the heart derived from?
The mesoderm
Where abouts within the embryo does the heart begin to develop?
Cranial to the neural plate
How does the heart begin to develop?
Begin to get cells forming blood islands which coalesce to form a tube like structure
How does the heart reach its final position
It undergoes lateral and longitudinal folding at the same time
What does lateral folding do?
Brings both ends of the endoderm together
what does longitudinal folding do?
bring the heart tube ventrally and more caudally and will move gradually into the thorax with further folding
What does the heart become closely associated with in folding?
The gut tube
What end of the heart tube is the inflow end and outflow end?
caudal (inflow end) to cranial end (outflow to vasculature)
What does the right horn of the sinus venosus give rise to?
becomes larger incorporated into wall of right atrium
What does the left horn of the sinus venosus give rise to?
becomes smaller retained on back of heart as coronary sinus
What does the atrium of the heart tube give rise to?
the trabeculated parts of both atria
What does the ventricle of the heart tube give rise to?
trabeculated part of the left ventricle
What does the bulbus cordis of the heart tube give rise to?
trabeculated part of right ventricle and outflow of both ventricle
what does the truncus arteriosus give rise to?
aorta and pulmonary trunk
When does the heart begin to fold and loop?
day 23
