Insulins Flashcards
Insulin acts on the liver to ______ storage of glucose as glycogen
increase
Insulin acts on the liver to ______ storage of glucose as glycogen
increase
What action does insulin have on muscle cells?
promotes protein and glycogen synthesis
Insulin ______ the circulation of fatty acids
reduces
also promotes the storage of triglycerides in adipose tissue
True or false:
Pork or beef insulin has a more rapid onset and shorter duration of action than human insulin
False
Human insulin is more rapid, lasts less time and is less antigenic
Humalog (lispro) and novolog (aspart) are examples of _____ acting insulin
rapid
rapid acting insulins have an onset of about ______ (minutes/hrs)
15 minutes
An example of a short acting insulin would be:
Regular
True or false:
Regular insulin is the only insulin available for IV use
TRUE
Insulin isophane (NPH) is an example of ________ acting insulin
intermediate
What is the onset of action of the intermediate acting insulins?
1 to 1.5 hours
Lantus (glargine) or Levemir (detemir) are examples of a(n) _____ acting insulin, with a duration of action of _______
long
24 hours or more
Preprandial injection of lispro is best timed __________ (minutes/hours) before meal times
15 minutes
What is a unique pharmacokinetic feature of insulin glargine?
It has no pronounced peak
True or false:
insulin detemir is a cloudy substance that is compatible for use with other insulins
False
Detemir is a clear solution that is not compatible with other insulins
