Insulin and glucagon regulation Flashcards
what is the structure of insulin
amino terminal Beta Chain
Carboxyterminal Alpha chain
Connective C chain
describe the process in which insulin is released
stimulated by elevated glucose and amino acid levels
voltage gated Calcium Channels open
influx of calcium into cell
insulin secreted by exocytosis through Glut transport protein
why is 2nd phase of insulin release prolonged
production of new insulin
what are the functions of insulin
slows metabolism
promote glucose conversion
enhance uptake if glucose
inhibit TAG breakdown
increase protein synthesis
what is the structure of glucagon
single chained polypeptide
what is the function of glucagon
mobalises glucose from hepatic glycogen
stimulates lipases
what are the different hormones secreted by the islets of langerhans and by which cells
glucagon (alpha cells)
insulin (beta cells)
somatostatin (gamma cells)
what is the function of somatostatin
inhibits the release of other hormones