Insulin and glucagon regulation Flashcards

1
Q

what is the structure of insulin

A

amino terminal Beta Chain
Carboxyterminal Alpha chain
Connective C chain

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2
Q

describe the process in which insulin is released

A

stimulated by elevated glucose and amino acid levels
voltage gated Calcium Channels open
influx of calcium into cell
insulin secreted by exocytosis through Glut transport protein

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3
Q

why is 2nd phase of insulin release prolonged

A

production of new insulin

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4
Q

what are the functions of insulin

A

slows metabolism
promote glucose conversion
enhance uptake if glucose
inhibit TAG breakdown
increase protein synthesis

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5
Q

what is the structure of glucagon

A

single chained polypeptide

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6
Q

what is the function of glucagon

A

mobalises glucose from hepatic glycogen
stimulates lipases

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7
Q

what are the different hormones secreted by the islets of langerhans and by which cells

A

glucagon (alpha cells)
insulin (beta cells)
somatostatin (gamma cells)

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8
Q

what is the function of somatostatin

A

inhibits the release of other hormones

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