Insulin Flashcards

1
Q

Where is insulin secreted into?

A

portal vein

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2
Q

What percentage of insulin is produced at a basal rate?

A

50%

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3
Q

What is the other 50% of insulin produced as?

A

a biphasic manner in response to a meal

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4
Q

Name some rapid acting insulins?

A

humalog
novorapid
apidra

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5
Q

Name some short acting insulins?

A

humulin S
actrapid
insuman rapid

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6
Q

Name some intermediate acting insulins?

A

insulintard
humulin 1
insuman basal

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7
Q

Name some long acting insulins?

A

lantus

Levemir

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8
Q

Name some rapid acting analogues-intermediate mixture?

A

Humalog 25 or 50

novomix 30

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9
Q

Name some short acting-intermediate mixture insulins?

A

humulin M3

insuman comb 15,25,30

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10
Q

How is insulin dose calculated?

A

0.3 units/kg of body weight

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11
Q

What is the peak after administration of insulin analogues?

A

60-90mins

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12
Q

What is the duration after administration of insulin analogues?

A

4-5hours

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13
Q

What is the peak after administration of soluble insulin?

A

2-4 hours

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14
Q

What is the duration after administration of soluble insulin?

A

8 hours

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15
Q

What is the target HbA1c for diabetics?

A

48mmol/L

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16
Q

What is the pre prandial blood glucose target?

A

4-7mmol/L

17
Q

What is the post prandial blood glucose target?

A

<10mmol/L

18
Q

What is the aim for BG when on IV insulin? (checked hourly)

A

5-12mmol/L

19
Q

What is the last resort treatment for T1DM?

A

pancreatic transplant or islet cell transplant