Hyperglyceamic Hyperosmolar Syndrome Flashcards

1
Q

What is HHS?

A

high blood glucose due to low insulin precipitated by high sugar intake

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2
Q

What is the difference between HHS and DKA?

A

no ketoacidosis in HHS

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3
Q

What are the risk factors for HHS?

A
older patients
young afrocarribeans
can be triggered by steroids and thiazide diuretics
fizzy drinks 
T1DM and T2DM
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4
Q

What are the biochemical signs to make a diagnosis of HHS?

A
hypovoleamia
hyperglycaemia >30mmol/L
bicarbonate >15mmol/L
venous pH <7.3
osmolarity >320 
mild ketoneamia <3mmol/L
high sodium
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5
Q

What is the typical presentation of HHS?

A

leg cramps
vision problems
confusion
dehydration

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6
Q

What is the osmolarity equation?

A

2 x [Na]

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7
Q

What is the treatment for HHS?

A

Diet
LMWH
IV insulin
0.9% saline IV

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8
Q

Describe the diagnostic criteria for alcohol induced ketoacidosis?

A

ketonaemia >3mmol/L
bicarbonate >15mmol/L
ketonuria >2
venous pH <7.3

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9
Q

What is the treatment for alcohol induced ketoacidosis?

A

IV pabrinex - vitmamins
IV fluids - dextrose (dont give dextrose first)
IV antiemetics
Insulin

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10
Q

Describe metabolic syndrome/syndrome X?

A
central obesity >30 plus 2 of:
triglycerides > 1.7mmol/L
BP > 130/85 - HYPERTENSION
HDL < 1.03/1.29
fasting glucose >5.6
T2DM
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