Insulin Flashcards
Pancreatic functions flow chart

Glucose Metabolism
Huge chart

Insulin Secretion from B-cells
What 3 things is insulin secretion regulated by

Insulin Secretion from B-cells
What is the most common regulator?
What causes glucose uptake into B-cells?
What traps sugar?
What follows?
Continues on next slide
elevated

Insulin Secretion from B-cells
ITs the chemical process of insulin release

6 actions of insulin on the liver
4 inhibitory
2 promoter

Actions of insulin on the liver chart form

Actions of insulin on Skeletal muscles
Promotes and Increases what?

Actions of insulin on Adipose
What does it increase?

DM pathophysiology
All tissues require?
What does insulin promote?

Dm glycogenolysis
Signals from starved cells

DM Hyperglycemia
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Dm: Gluconeogenesis and Azoturia
What does continued shortage of glucose within cells cause?
How is Azoturia caused?

Dm hyperlipidemia
What does lack of intracellular glucose also increase?

Dm ketogenesis
What is it? Accelerated what?

DM sorbitol
Glucose to this with what enzyme?
How are glucose spikes dealt with in the body?

DM sorbitol
If there is repeated spiking what happens to sorbitol?
What are some diseases?

DM1 and DM2 Chart
comparison

Insulin has two chains
B and A Chain
Insulin preparations
Regular Insulin
5
and
Recombinant
3

Regular Insulin preparations
Immunogenicity from with different animal uses

What three things are used to classify insulins?
Categories for DOA 4 name the ones in each

Crystalline Zinc insulin
DOA?
What is added to improve stability?

What happens to Crystalline Zinc after SC injection? What does this give in terms of activity?
In emergencies can be given as?

























