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MDCM626 > Calcium Modulation > Flashcards

Calcium Modulation Flashcards

1
Q

Bone and Calcium

Two components of bone

What two cell types control bone formatIon? What are these cell types involved in?

A
  1. Hydroxyapatite
  2. Fibrous protein mainly collagen
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2
Q

Hormonal Regulations of Serum Calcium Levels

What are the 3 hormones

A
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3
Q

Calcitonin where is it synthesized?

What is required for activity?

A
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4
Q

Calcitonin is secreted in response to?

CT ____ serum Ca2+ by 3 things:

A
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5
Q

Parathyroid Hormone

Synthesis where?

Where does activity reside?

A
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6
Q

PTH is secreted in response to ____ serum Ca2+

PTH ____ serum Ca2+ by: 4 things

A
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7
Q

Vit D

In the liver what is cholesterol modified to?

A
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8
Q

Bioactivation of Vit D

What 2 oxidative steps does D3 undergo?

What is the storage form of Vit D?

What are the differences of that and D3

A
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9
Q

Bioactivation of Vit D

Second oxidation in response to?

What is the active form of Vit D?

A
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10
Q

Bioactivation rxns

A
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11
Q

Vit D

____ works in concert with PTH to do what 3 things?

A
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12
Q

What does high serum Ca2+ activate?

A
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13
Q

Vit D Biosynth and Inactivation Chart

A
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14
Q

Summary of Serum Ca2+ Hormonal Control

Calcitonin ____ Serum Ca2+ in 3 ways

PTH ____ serum Ca2+ in 4 ways

Vit D ____ serum Ca2+ in 3 ways

A
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15
Q

Calcium homeostasis related disorders

Disorders leading to?

or ____?

And disorders of?

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16
Q

Reasons for having hypocalcemia

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17
Q

hypercalcemia examples

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18
Q

Bone remodeling examples

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19
Q

Hypocal tx: 2 things

Hyper Tx: 7 things

Remodeling Tx: 7

A
20
Q

Drugs for Tx calcium homeostasis related disorders

6 agents

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MDCM626 (26 decks)

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