Inmunogenética Flashcards

1
Q

Porcentaje de estimación en la heredabilidad de AR

A

60%

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2
Q

Contribución de HLA a la heredabilidad de AR

A

11 a 37%

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3
Q

Tipo de HLA asociado con AR

A

HLA-DR4

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4
Q

Subtipos de HLA-DR4 relacionados con AR

A

Dw4, Dw14, Dw15

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5
Q

Genes protectores del desarrollo de AR

A

Alelo DR2

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6
Q

Enfermedad más fuertemente asociada a HLA

A

Espondilitis Anquilosante (HLA-B27) en el 90% de los px, en 3-8% de la pob sana

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7
Q

Prevalencia de HLA-B27 en uveitis

A

25%, asociado tmb con haplotipo HLA-DR8

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8
Q

Autoanticuerpos en SS

A

Anti Ro (HLA-DRB1.03)
Anti-La (HLA-DRB 1. 02)
Anti-Sm

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9
Q

HLA asociado con EMTC

A

HLA-DRB1.04

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