Anticuerpos Antinucelares Flashcards

1
Q

Sensibilidad y especificidad de anti-Sm (moteado grueso) en LEG

A

30 sensibilidad

90% de especificidad

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2
Q

Prevalencia de AAN en LEG

A

> 95% en afección ORGÁNICA

60% en afección periférica

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3
Q

AAN encontrado en nefritis lúpica

A

Patron homogéneo y periférico (anti-dsDNA)

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4
Q

Patron moteado fino y grueso en Lupus?

A

Moteado fino es Anti-SSA/Ro (neonatal y cutáneo)

Moteado grueso en Anti-Sm (patognomónico)

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5
Q

Prevalencia de ANN positivos en MII

A

50-80%

Anti sintetasa de ARN

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6
Q

Anti-p155

A

Dermatomiositis y cáncer

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7
Q

Artritis idiopática juvenil con AAN + se asocia a:

A

Uveítis

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8
Q

Positividad de ANN en escleroderma

A

85-99%

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9
Q

Patrón nucleolar moteado

A

Scl-70 (Escleroderma VDifusa)

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10
Q

Patrón moteado fino

A

Anti Ro/La

*SSjogren y LEG cutáneo difuso y neonatal

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11
Q

Patrón moteado grueso

A

U1-RNP (EMTC)

Anti-Sm (LEG específico)

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12
Q

Patrón citoplásmatico moteado

A

Anti-Jo1 (Anti sintetasa)

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13
Q

Patrón citoplasmático homogéneo

A

Anti-P (NL)

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