Initial Pharmacodynamic Actions of Addictive Drugs Flashcards
1
Q
Cocaine
A
Target DAT (+ SERT-NET)
MOA Inhibitor
DA effect Blocks DA Uptake
2
Q
Alcohol
A
Target GABA-A channel
MOA Complex-facilitate
DA effect Excitation, disinhibition
3
Q
Methamphetamine
A
Target DAT (+ SERT-NET, VMAT)
MOA Reverses transporter
DA effect DA releaser
4
Q
Opioids
A
Target u opioid receptor [Gi/o
MOA Agonist
DA effect Disinhibition
5
Q
Nicotine
A
Target Nicotinic receptor
MOA Agonist
DA effect Excitation
6
Q
x
A
Target
MOA
DA effect
7
Q
Nicotine
Target Nicotinic receptor
MOA Agonist
DA effect _________
A
Excitation
8
Q
x
A
Target
MOA
DA effect
9
Q
x
A
Target
MOA
DA effect
