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Mo-Neuro 4 > Anxiolytic Agents > Flashcards

Anxiolytic Agents Flashcards

1
Q

Antidepressants

A

1st line agents for most anxiety disorders

NO NDRIs tho

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2
Q

Buspirone 5HT

A

Weaker anxiolytic effect than benzodiazepines, but fewer side effects

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3
Q

Benzodiazepines* GABA

A

Declining use due to abuse potential - used in acute and situational anxiety

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4
Q

Barbiturates* GABA

A

Rarely used for anxiety  low safety margin - drug interactions - high abuse potential

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5
Q

Sedative drugs

A

decrease activity, moderate excitement, and calm the recipient

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6
Q

Hypnotic drugs

A

Produce drowsiness and facilitate the onset and maintenance of sleep

Resembles natural sleep and from which the recipient can be easily aroused

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7
Q

5HT drugs

A

SSRi

SNRi

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8
Q

Buspirone

A

5ht partial

Possible side effects: HA, Lightheadedness, Nervousness, Excitement

May treat: Intellectual disability, Depressive Disorder

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9
Q

Sedative - Hypnotic Agents*

A

Produce graded dose-dependent CNS depressant effects

Distinct mechanism of depressant action: augment GABA inhibition and/or inhibit glutamate excitation

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10
Q

Hypnotic drugs

A

Produce drowsiness and facilitate the onset and maintenance of sleep

Resembles natural sleep and from which the recipient can be easily aroused

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11
Q

Sedtavitve hypnotics do

A

↑ GABA or ↓ Glu

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12
Q

Benzos dont work w/o

A

GABA (at a low dose)

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13
Q

Bdz+ gaba–>

A

↑↑ Cl–> ↓ Em

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14
Q

High doses of ETOH and barbs can do?

A

Open Cl- directly w/o gaba

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15
Q

BDZs enhance channel opening only in presence of

A

GABA

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16
Q

_____ prolong channel opening in presence of GABA and at higher doses open channel directly

A

BARBs

17
Q

Benzos dont do

A

anesthesia

Can be an additional one though- anastia adjunct

18
Q

Barbs

A

Can do ana

19
Q

Props

A

Can do ana

20
Q

GABA- r is

A

2 alpha
2 beta
1 gama

21
Q

Benzo alone are

A

safe

bdz + etoh= lethal

22
Q

Drugs for Anxiety

A 
Alprazolam (Xanax®)
 Lorazepam (Ativan®)
 Clonazepam (Klonopin®)
 Diazepam (Valium®)
 Busprione (Buspar®)

Mo-Neuro 4 (37 decks)

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