Antidepressant Agents Flashcards by MO ROUTH

NT: Monoamine Neurotransmitter Brainstem Nuclei
NE–> Locus Ceruleus
5HT –> Raphe
DA–> VTA

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Initial observation: Reserpine depleted brain NE and 5HT –>

induced depression

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Additional support: Effective antidepressant drugs share property to ___________

enhance NE-5HT-(DA) availability in synapse

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Antidepressant Agents

Sertraline (Zoloft®) SSRI
 Citalopram (Celexa®)  SSRI
Escitalopram (Lexapro®)  SSRI
Fluoxetine (Prozac®)  SSRI
Venlafaxine (Effexor XR®) SNRI
Trazodone  5HT partial agonist-SSRI
Duloxetine (Cymbalta®)  SNRI
Paroxetine (Paxil®) / (Paxil CR®)  SSRI
Amitriptyline (Elavil®)  TCAD
Bupropion (Wellbutrin XL®) NDRI

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Mirtazapine (Remeron®)

α2 antagonist

Phenelzine MAOI

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Sertraline (Zoloft®)

SSRI

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Citalopram (Celexa®)

SSRI

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Escitalopram (Lexapro®)

SSRI

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Fluoxetine (Prozac®)

SSRI

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Bupropion (Wellbutrin XL®)

NDRI

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Amitriptyline (Elavil®)

TCAD

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Paroxetine (Paxil®) / (Paxil CR®)

SSRI

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Trazodone

5HT partial agonist-SSRI

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Duloxetine (Cymbalta®)

SNRI

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Venlafaxine (Effexor XR®)

SNRI

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Fluoxetine (Prozac®)

SSRI

Brainscape's Knowledge GenomeTM

Antidepressant Agents Flashcards

Brainscape's Knowledge Genome^TM