Inheritance Extra practice Flashcards
Phenotypic Plasticity
An organism’s ability to change its phenotype in response to environmental changes without requiring genetic mutations
Homozygous and Heterozygous
Homozygous have 2 identical alleles of a gene while Heterozygous have 2 different alleles of a gene
Inheritance Diseases Examples
Huntington - Autosomal Dominant
Cystic Fibrosis and Phenylketonuria - Autosomal Recessive
Sickle Cell Anemia - Autosomal Co-dominance
Hemophilia and Red-green Color Blindness - Sex-linked Recessive
Carrier
An individual that has one copy of a recessive allele that causes a genetic disease in individuals who are homozygous for this allele
Parental VS Recombinant Geno and Phenotypes
Phenotypes of offspring often resemble (at least 1) parents
Phenotypes of offspring differ from both parents
Genotype shows that traits are either dominant or recessive
Genotype shows that one trait is dominant and one recessive
The Fundamental Laws of Inheritance
The Law of Segregation: Pairs of alleles of a gene separate during gamete formation
The Law of Independent Assortment: Two or more pairs of alleles segregate independently of each other as a result of meiosis in Metaphase I
The Law of Dominance: An organism with alternate forms of a gene will express the dominant form
Unlinked Genes
Genes found on separate chromosome pair
Chromosomes segregate independently due to meiosis
Recombination is due to crossing over and independent assortment
Gametes will include parental chromosomes and recombinants, which take up about 50% of the offspring
Represented as AaBb
Skin Color Factors
Polygenic Inheritance
Environmental Factors
Autosomal Dominant
Appears almost in both males and females equally
All affected individuals must have an affected parent
Trait doesn’t skip generation
Unaffected parents must produce unaffected offspring
Affected parents can have unaffected child
Autosomal Recessive
Appears almost in both males and females equally
Unaffected parents can have unaffected offspring
Trait skips generation
Affected parents must produce affected offspring
Sex-linked Recessive
Common in males
If a female shows a trait, then all her sons and father must
An unaffected mother can have affected son if she is a carrier
Crossing 2 Homo and Hetero
Crossing 2 Homozygous, ratio is 1:0
Crossing 2 Heterozygous, ratio is 3:1
Crossing hetero with homo recessive, ratio is 1:1
Ratio of Unlinked Genes
Hetero with Hetero = 9:3:3:1
Hetero with Homo recessive = 1:1:1:1
Sex-linked Dominant
Common in females
If a male shows a trait, then all his daughters and mother must
An unaffected mother can not have affected sons
Difference between DNA Segregation and Independent Assortment
Pairs of alleles of a gene separate randomly during gamete formation
The independent segregation of the alleles of two genes of each other so that the outcome with each gene has no effect on the outcome of the other
Blood Groups and Alleles
A - I^A
B - I^B
IA - I^AI^B
O - i
A and B code for enzymes that add specific sugars to a glycoprotein on the RBC
Linked Genes
Genes are found on the same chromosome pair
Chromosomes don’t assort independently and tend to be inherited together
Recombination only occurs if crossing over occurs
The closer two alleles are on a chromosome, the less likely crossing over will occur, vice versa
Have fewer recombinants than unlinked genes
Represented as AB//ab
Co-dominance
Two dominant alleles of the same gene are present and contribute to the phenotype which violates the Law of Dominance
Gene that Develops Testes
SRY
Discontinuous VS Continuous Variation
Results in limited amount of phenotypes and no in-betweens
Results in range of phenotypes with in-betweens
Tend to be qualitative
Tend to be quantitative
Controlled by one gene
Controlled by multiple genes
Unaffected by environment
Affected by environment
Shown in a bar graph with separate bars
Bell shaped curve
Example is human blood group
Example is skin color
Incomplete Dominance
One allele for a trait is not expressed completely over its paired allele, thus having an intermediate where neither allele is formed