Inheritance Extra practice Flashcards

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1
Q

Homozygous and Heterozygous

A

Homozygous have 2 identical alleles of a gene while Heterozygous have 2 different alleles of a gene

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2
Q

Carrier

A

An individual that has one copy of a recessive allele that causes a genetic disease in individuals who are homozygous for this allele

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3
Q

Phenotypic Plasticity

A

An organism’s ability to change its phenotype in response to environmental changes without requiring genetic mutations

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4
Q

The Fundamental Laws of Inheritance

A

The Law of Segregation: Pairs of alleles of a gene separate during gamete formation

The Law of Independent Assortment: Two or more pairs of alleles segregate independently of each other as a result of meiosis in Metaphase I

The Law of Dominance: An organism with alternate forms of a gene will express the dominant form

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5
Q

Crossing 2 Homo and Hetero

A

Crossing 2 Homozygous, ratio is 1:0

Crossing 2 Heterozygous, ratio is 3:1

Crossing hetero with homo recessive, ratio is 1:1

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6
Q

Incomplete Dominance

A

One allele for a trait is not expressed completely over its paired allele, thus having an intermediate where neither allele is formed

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7
Q

Co-dominance

A

Two dominant alleles of the same gene are present and contribute to the phenotype which violates the Law of Dominance

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8
Q

Blood Groups and Alleles

A

A - I^A
B - I^B
IA - I^AI^B
O - i

A and B code for enzymes that add specific sugars to a glycoprotein on the RBC

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9
Q

Gene that Develops Testes

A

SRY

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10
Q

Autosomal Dominant

A

Appears almost in both males and females equally

All affected individuals must have an affected parent

Trait doesn’t skip generation

Unaffected parents must produce unaffected offspring

Affected parents can have unaffected child

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11
Q

Autosomal Recessive

A

Appears almost in both males and females equally

Unaffected parents can have unaffected offspring

Trait skips generation

Affected parents must produce affected offspring

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12
Q

Sex-linked Dominant

A

Common in females

If a male shows a trait, then all his daughters and mother must

An unaffected mother can not have affected sons

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13
Q

Sex-linked Recessive

A

Common in males

If a female shows a trait, then all her sons and father must

An unaffected mother can have affected son if she is a carrier

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14
Q

Discontinuous VS Continuous Variation

A

Results in limited amount of phenotypes and no in-betweens
Results in range of phenotypes with in-betweens

Tend to be qualitative
Tend to be quantitative

Controlled by one gene
Controlled by multiple genes

Unaffected by environment
Affected by environment

Shown in a bar graph with separate bars
Bell shaped curve

Example is human blood group
Example is skin color

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15
Q

Skin Color Factors

A

Polygenic Inheritance

Environmental Factors

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16
Q

Difference between DNA Segregation and Independent Assortment

A

Pairs of alleles of a gene separate randomly during gamete formation

The independent segregation of the alleles of two genes of each other so that the outcome with each gene has no effect on the outcome of the other

17
Q

Unlinked Genes

A

Genes found on separate chromosome pair

Chromosomes segregate independently due to meiosis

Recombination is due to crossing over and independent assortment

Gametes will include parental chromosomes and recombinants, which take up about 50% of the offspring

Represented as AaBb

18
Q

Linked Genes

A

Genes are found on the same chromosome pair

Chromosomes don’t assort independently and tend to be inherited together

Recombination only occurs if crossing over occurs

The closer two alleles are on a chromosome, the less likely crossing over will occur, vice versa

Have fewer recombinants than unlinked genes

Represented as AB//ab

19
Q

Ratio of Unlinked Genes

A

Hetero with Hetero = 9:3:3:1

Hetero with Homo recessive = 1:1:1:1

20
Q

Parental VS Recombinant Geno and Phenotypes

A

Phenotypes of offspring often resemble (at least 1) parents
Phenotypes of offspring differ from both parents

Genotype shows that traits are either dominant or recessive
Genotype shows that one trait is dominant and one recessive

21
Q

Inheritance Diseases Examples

A

Huntington - Autosomal Dominant

Cystic Fibrosis and Phenylketonuria - Autosomal Recessive

Sickle Cell Anemia - Autosomal Co-dominance

Hemophilia and Red-green Color Blindness - Sex-linked Recessive