Infliximab Flashcards

1
Q

What are the primary therapeutic uses of Infliximab?

A

used to treat autoimmune conditions such as rheumatoid arthritis, Crohn’s disease, ulcerative colitis, ankylosing spondylitis, and psoriasis.

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2
Q

How is Infliximab administered?

A

administered via intravenous infusion, typically over a period of not less than 2 hours.

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3
Q

What are common adverse effects of Infliximab?

A

infusion-related reactions (fever, chills, itching, hives, rash, dizziness, fainting, lightheadedness), increased risk of infections, and potential reactivation of latent infections like tuberculosis

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4
Q

What serious infections are associated with Infliximab use?

A

linked to serious infections, including tuberculosis, bacterial sepsis, and invasive fungal infections

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5
Q

What pre-treatment evaluations are necessary before starting Infliximab?

A

screened for latent tuberculosis and hepatitis B prior to initiating therapy

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6
Q

What are the contraindications for using Infliximab?

A

known hypersensitivity to Infliximab or its components, and active infections such as sepsis

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7
Q

How should patients be monitored during Infliximab therapy?

A

signs of infection, infusion-related reactions, and periodic blood tests to assess white and red blood cell counts

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8
Q

Are there any considerations regarding pregnancy and breastfeeding with Infliximab?

A

may pass into breast milk, but it is unlikely to harm a nursing infant. Patients should consult their healthcare provider regarding use during pregnancy and breastfeeding.

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9
Q

What should patients avoid while taking this med?

A

live vaccines

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