Cyclosporine Flashcards
What is the therapeutic use?
Used to prevent organ rejection in transplant recipients and treat autoimmune diseases like rheumatoid arthritis and psoriasis.
How is Cyclosporine administered?
Given orally or intravenously
What are common adverse effects of Cyclosporine?
Nephrotoxicity, hypertension, gingival hyperplasia, hepatotoxicity, increased risk of infections
What drugs interact with Cyclosporine and increase toxicity risk?
NSAIDs, aminoglycosides, antifungals (ketoconazole), macrolide antibiotics (erythromycin), and grapefruit juice
What should patients avoid while taking Cyclosporine?
Alcohol, live vaccines, excessive sun exposure, and high-potassium foods
What is the mechanism of action of Cyclosporine?
it inhibits T-cell activation to suppress the immune response and prevent organ rejection.
What are the nursing considerations for Cyclosporine therapy?
Monitor renal/liver function, assess for infection, check blood pressure, educate on oral hygiene, and reinforce medication adherence.
