Inflammatory Bowel Disease

Question 1

Where does crohns disease effect

Answer 1

Anywhere in GI tract

Typically patchy

Question 2

Where does ulcerative colitis effect

Answer 2

Starts at rectum and moves back along colon

Only in colon

Question 3

How does the bowel appear in microscopic colitis

Answer 3

Normal

Question 4

How is microscopic colitis diagnosed

Answer 4

By histology

Question 5

Symptom of microscopic colitis

Answer 5

Non bloody diarrhoea

Question 6

Which migrating population is at increased risk of crohn’s

Answer 6

Male migrating Asians

Question 7

Symptoms of ulcerative colitis

Answer 7

Bloody diarrhoea
Fatigue
weight loss
abdominal pain

Question 8

What is proctitis

Answer 8

Inflammation of the rectum

Question 9

Symptoms of proctitis

Answer 9

Change in bowel habit (frequency and urgency)

Diarrhoea with mucus and blood

Question 10

Other cause of proctitis instead of IBD

Answer 10

STI

Question 11

Investigations for IBD

Answer 11

Bloods (CRP, WBC, Platlets [high], Albumin [low])

Faecal sample (infection)

Faecal calprotectin (High)

Colonoscopy with biopsies (gold standard if IBD suspected)

Question 12

What level of faecal calprotectin is highly suggestive of IBD

Answer 12

> 200 ug/g

Question 13

How many stool cultures to diagnose c.diff

Answer 13

4

Question 14

Symptoms of Crohn’s disease

Answer 14

Abdominal pain
Diarrhoea
Weight loss 
fatigue
Malabsorption

Question 15

Investigations for suspected Crohn’s disease

Answer 15

Bloods for inflammation 
Stool sample (infection)
faecal calprotectin
Colonoscope (gold standard)
MRI for small intestine

Question 16

First line treatment of ulcerative colitis

Answer 16

5ASA’s