Inflammation / Healing Process - 1 Flashcards

0
Q

overuse, cyclic loading, friction injuries. small stresses that cause injury over time

A

microtrauma

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1
Q

large injury that results in failure of musculoskeletal structures

A

macrotrauma

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2
Q

primary injury can cause swelling and ultrastructural changes like damaging the blank of the ankle

A

ligaments

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3
Q

two causes of secondary injury

A

enzymatic injury, metabolic injury

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4
Q

example of an enzymatic secondary injury

A

lysosomal mechanism (eating good tissue)

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5
Q

example of metabolic injury

A

inadequate waste removal

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6
Q

inflammation is a coordinated chemical response with blank

A

vascularity

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7
Q

heat and redness are caused by increased blank

A

vascularity

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8
Q

swelling is caused by blockage of blank drainage

A

lymphatic

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9
Q

pain is caused by a physical blank or blank irritation

A

pressure, chemical

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10
Q

loss of function is caused by blank

A

pain/swelling

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11
Q

activate blank receptors with joint mobes to inhibit blank receptors

A

mechano, pain

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12
Q

blood clotting aka

A

hemostasis

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13
Q

protective –> controlled motion –> return to function

A

aka inflammation, proliferation, maturation

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14
Q

vasoconstriction in injured vessels is the blank response to injury

A

vascular

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15
Q

protein rich fluid escapes into surrounding tissue which pulls blank with it due to being blank

A

water, hydrophilic

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16
Q

pressure exerted by a column of water

A

hydrostatic pressure

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17
Q

pressure resulting from attraction of fluid by free proteins

A

osmotic pressure

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18
Q

basophils, eosinophils, neutrophils are all pretty important in blank

A

inflammation

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19
Q

release antibodies into bloodstream

A

b lymphocytes

20
Q

cell deprived of oxygen

A

hypoxia

21
Q

when hypoxia occurs in cells after injury, blank metabolism kicks in, so the blank pump slows down which increases cellular blank

A

anaerobic, sodium potassium, acidosis

22
Q

removal of noxious stimuli, growth of capillary beds, collagen forms, easily injured tissue

A

proliferation phase

23
Q

fibroblasts produce blank

A

collagen

24
Q

fibroblast growth occurring in connective tissue

A

fibroplasia

25
Q

composed of capillaries, fibroblasts, and myofibroblasts

A

granulation tissue

26
Q

initially type blank collagen is formed

A

3

27
Q

wound contraction that pulls epithelial layer inwards

A

myofibroblasts

28
Q

wound closure takes about blank days in muscle/skin

A

5-8

29
Q

wound closure takes blank days in tendon and ligament

A

3-6 weeks

30
Q

wound contraction begins about blank days after injury

A

5

31
Q

growth of new blood vessels during proliferation

A

angiogenesis

32
Q

longest phase in healing process and can last more than a year

A

maturation

33
Q

goal of maturation pt

A

return to normal funciton

34
Q

collagen provides extracellular blank

A

framework

35
Q

synthesis of scar dominates over lysis will result in blank or blank scars

A

hypertrophic, keloid

36
Q

a red scar means more blank is occurring

A

healing

37
Q

restarting acute phase without getting out of it

A

recurrent inflammation

38
Q

healing where scar tissue restores normal function

A

acceptable

39
Q

healing where injury is more likely

A

minimal

40
Q

healing where no tissue is really repaired

A

failed

41
Q

collagen goes from type 3 to type 1 during this healing phase

A

maturation

42
Q

tendon healing is only blank to blank

A

minimal, acceptable

43
Q

inflammation occurs in blank tissue

A

vascularized

44
Q

capillary filtration pressure formula

A

(CHP + TOP) - (THP + COP)

45
Q

CHP is

A

capillary hydrostatic pressure

46
Q

top is

A

tissue osmotic pressure

47
Q

thp is

A

tissue hydrostatic pressure

48
Q

cop is

A

capillary osmotic pressure