Inflammation / Healing Process - 1 Flashcards

0
Q

overuse, cyclic loading, friction injuries. small stresses that cause injury over time

A

microtrauma

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1
Q

large injury that results in failure of musculoskeletal structures

A

macrotrauma

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2
Q

primary injury can cause swelling and ultrastructural changes like damaging the blank of the ankle

A

ligaments

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3
Q

two causes of secondary injury

A

enzymatic injury, metabolic injury

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4
Q

example of an enzymatic secondary injury

A

lysosomal mechanism (eating good tissue)

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5
Q

example of metabolic injury

A

inadequate waste removal

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6
Q

inflammation is a coordinated chemical response with blank

A

vascularity

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7
Q

heat and redness are caused by increased blank

A

vascularity

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8
Q

swelling is caused by blockage of blank drainage

A

lymphatic

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9
Q

pain is caused by a physical blank or blank irritation

A

pressure, chemical

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10
Q

loss of function is caused by blank

A

pain/swelling

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11
Q

activate blank receptors with joint mobes to inhibit blank receptors

A

mechano, pain

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12
Q

blood clotting aka

A

hemostasis

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13
Q

protective –> controlled motion –> return to function

A

aka inflammation, proliferation, maturation

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14
Q

vasoconstriction in injured vessels is the blank response to injury

A

vascular

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15
Q

protein rich fluid escapes into surrounding tissue which pulls blank with it due to being blank

A

water, hydrophilic

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16
Q

pressure exerted by a column of water

A

hydrostatic pressure

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17
Q

pressure resulting from attraction of fluid by free proteins

A

osmotic pressure

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18
Q

basophils, eosinophils, neutrophils are all pretty important in blank

A

inflammation

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19
Q

release antibodies into bloodstream

A

b lymphocytes

20
Q

cell deprived of oxygen

21
Q

when hypoxia occurs in cells after injury, blank metabolism kicks in, so the blank pump slows down which increases cellular blank

A

anaerobic, sodium potassium, acidosis

22
Q

removal of noxious stimuli, growth of capillary beds, collagen forms, easily injured tissue

A

proliferation phase

23
Q

fibroblasts produce blank

24
fibroblast growth occurring in connective tissue
fibroplasia
25
composed of capillaries, fibroblasts, and myofibroblasts
granulation tissue
26
initially type blank collagen is formed
3
27
wound contraction that pulls epithelial layer inwards
myofibroblasts
28
wound closure takes about blank days in muscle/skin
5-8
29
wound closure takes blank days in tendon and ligament
3-6 weeks
30
wound contraction begins about blank days after injury
5
31
growth of new blood vessels during proliferation
angiogenesis
32
longest phase in healing process and can last more than a year
maturation
33
goal of maturation pt
return to normal funciton
34
collagen provides extracellular blank
framework
35
synthesis of scar dominates over lysis will result in blank or blank scars
hypertrophic, keloid
36
a red scar means more blank is occurring
healing
37
restarting acute phase without getting out of it
recurrent inflammation
38
healing where scar tissue restores normal function
acceptable
39
healing where injury is more likely
minimal
40
healing where no tissue is really repaired
failed
41
collagen goes from type 3 to type 1 during this healing phase
maturation
42
tendon healing is only blank to blank
minimal, acceptable
43
inflammation occurs in blank tissue
vascularized
44
capillary filtration pressure formula
(CHP + TOP) - (THP + COP)
45
CHP is
capillary hydrostatic pressure
46
top is
tissue osmotic pressure
47
thp is
tissue hydrostatic pressure
48
cop is
capillary osmotic pressure