Inflammation and Repair Part II Flashcards

1
Q

Examples of injury to oral soft tissue

A

***Aspirin/Phenol/Chemical burns
Meth use
Lesions from cocaine use
Self-induced injuries
Hematoma
Traumatic ulcer
Frictional keratosis
Linea Alba
Nicotinic Stomatitis
Tobacco pouch keratosis
Traumatic neuroma
Amalgam tattoo
Melanosis
Solar cheilitis
Mucocele
Saliolith

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2
Q

How is “meth mouth” categorized?

A

Rapid destruction of teeth as a result of:
-Meth acid content
-Decreased salivary flow
-Cravings for high sugar beverages
-Lack of oral hygiene

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3
Q

Characteristics of aspirin burns

A

Tissue becomes necrotic and white
Surface may slough off leaving a painful ulcer
Usually heals in 7 to 21 days

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4
Q

What are some dental materials that may cause chemical burns

A

Phenol- cavity sterilizing agent and cauterizing agent
Sodium hypochlorite
Ferric sulfate
Eugenol
Formocresol

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5
Q

How may electric burns occur in the mouth?

A

When infants or young children chew on electrical cords
Can cause permanent disfigurement and scarring
Treatment includes oral surgery, orthodontics and plastic surgery

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6
Q

What causes thermal burns?

A

Hot food- soup or cheese on pizza

Also from products containing hydrogen peroxide or eugenol

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7
Q

Lesions associated with cocaine use

A

Lesions on midline of hard palate associated with smoking crack cocaine- ulcers to keratotic lesions

Necrotic ulcers of tongue and epiglottis seen in users who freebase

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8
Q

What are some lesions that can occur as self-induced injuries?

A

Chronic lip, cheek or tongue biting
Trauma to gingiva from fingernails

Range from ulceration to epithelial hyperplasia to hyperkeratosis

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9
Q

What can lead to traumatic ulcers?

A

Cheek, lip or tongue biting
Denture irritation
Mucosal injury
Overzealous brushing

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10
Q

What is a traumatic granuloma?

A

Results from persistent trauma
Appears as a hards, raised lesion
Heals rapidly after biopsy

May resemble squamous cell carcinoma

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11
Q

What is a hematoma?

A

Accumulation of blood within tissue as a result of trauma

Frequently seen in buccal or labial mucosa

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12
Q

What is frictional keratosis?

A

Form of hyperkeratosis
Caused by chronic rubbing or friction against and oral mucosal surface

Opaque and white- resembles a callus
Treatment includes removing the cause of friction- must be differentiated from idiopathic leukoplakia

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13
Q

What is nicotine stomatitis?

A

Benign lesion associated with pipe, cigar or cigarette smoking
Initially appears as erythema
Increases in opacity as keratinization occurs
Raised red areas occur at openings of ducts and salivary glands

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14
Q

Characteristics of smokeless tobacco keratosis

A

White lesion located where chewing tobacco is placed, most often in mucobuccal fold
Early= granular/wrinkled
Long standing= Opaque white and corrugated

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15
Q

What is a traumatic neuroma?

A

Lesion caused by injury to a peripheral nerve

Treatment is surgical excision

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16
Q

What are palisaded encapsulated neuroma (PEN)?

A

Benign lesion presenting as a mucosal nodule- painless
Well circumscribed and contains nerve tissue surrounded by fibrous CT

Reactive hyperplastic lesion

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17
Q

When can amalgam tattoos occur?

A

During placement or removal of amalgam restorations or during extractions

Most common on the gingiva or edentulous alveolar ridge

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18
Q

What is melanosis?

A

Normal physiologic pigmentation of oral mucosa
-Can be genetic
-Or as a result of inflammation

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19
Q

What is solar cheilitis? (actinic cheilitis)

A

Breakdown of tissue of the lips caused by sun exposure
-lips are dry and cracked
-vermillion border is pale

Alcohol and tobacco use can increase risk of squamous cell carcinoma

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20
Q

What is a mucocele?

A

Lesion formed when a salivary duct is severed and mucous salivary gland secretion spills into adjacent CT
-Fluid-filled and cyst-like
Not a true cyst

21
Q

What is a ranula?

A

Unilateral mucocele-like lesion that forms on the floor of the mouth

Associated w/ submandibular and sublingual ducts

22
Q

What is a sialolith?

A

Salivary gland stone

23
Q

What is necrotizing sialometaplasia?

A

Benign condition of salivary glands
-Moderately painful swelling/ulceration
-Thought to result from a blockage of blood supply resulting in salivary gland necrosis

24
Q

What is acute and chronic sialadenitis?

A

Painful swelling of salivary gland caused by obstruction

25
Q

Examples of reactive connective tissue hyperplasia

A

Pyogenic granuloma
Giant cell granuloma
Irritation fibroma
Denture-induced fibrous hyperplasia
Papillary hyperplasia of the palate
Gingival enlargement
Chronic hyperplastic pulpitis

26
Q

What does reactive connective tissue hyperplasia consist of?

A

Proliferating, exuberant granulation tissue and hyperplastic fibrous CT

27
Q

What is a pyogenic granuloma?

A

Proliferation of CT containing numerous BV as a result of trauma

Not a true granuloma

28
Q

Appearance of pyogenic granuloma

A

Ulcerated and soft on palpation
Bleeds easily
Dark red to purple
Elevated- sessile or pedunculated
Usually on gingiva
Varies in size

In pregnant women, called pregnancy tumor

29
Q

What is peripheral giant cell granuloma?

A

A lesion that contains many multinucleated giant cells, well-vascularized connective tissue, RBCs, and chronic inflammatory cells

Resembles pyogenic granuloma

30
Q

What is peripheral ossifying fibroma?

A

Exophytic lesion usually emanating from the interdental papilla

31
Q

What is the most commonly found mass on the gingiva? What is it caused by?

A

Fibroma

Caused by trauma

32
Q

How do fibromas appear?

A

Broad based, exophytic lesion composed of dense, scar-like CT w/ few blood vessels

33
Q

How does denture-induced fibrous hyperplasia occur?

A

From ill-fitting dentures
Occurs in elongated folds of tissue adjacent to the denture

34
Q

What is inflammatory hyperplasia of the palate?

A

Induced by dentures

Appears on palatal mucosa and covered by multiple erythematous papillary projections. “cobblestones”

35
Q

What is gingival enlargement?

A

Increase in bulk of free and attached gingiva, especially interdental papilla

Rounded margins, color variations. Generalized or localized

36
Q

What causes gingival enlargement?

A

Local irritants
Hormonal changes
Drugs
Hereditary conditions
Idiopathic factors
Leukemia

37
Q

What is chronic hyperplastic pulpitis?

A

Excessive proliferation of chronically inflamed dental pulp tissue
-Occurs in teeth with large, open carious lesions often in molars
-Usually asymptomatic

38
Q

Types of inflammatory periapical lesions

A

Periapical abscess
Dental or periapical granuloma
Radicular cysts
Resorption of teeth
Focal sclerosing osteomyelitis
Alveolar osteitis (dry socket)

39
Q

What can result from caries or trauma?

A

Inflammation
Infection
Chronic hyperplastic pulpitis
Necrosis of the pulp

40
Q

What part of the tooth anatomy allows inflammation to begin in pulp and extend to the periapical area?

A

Accessory canals on the lateral portion of root

41
Q

How are periapical abscesses characterized?

A

Purulent exudate surrounded by CT containing neutrophils and lymphocytes
-Severe pain
-Tooth may extrude from socket
-May or may not test positive w/ electric pulp testing

42
Q

Why do fistulas form?

A

As a way for purulent exudate to be drained

43
Q

What is a periapical granuloma?

A

Localized mass of chronically inflamed granulation tissue that forms at the opening of the pulp canal, generally at the apex of a non-vital tooth root

44
Q

Characteristics of periapical granulomas

A

-Chronic process
-Most are asymptomatic
-May be sensitive to pressure or percussion
-Tooth may be slightly extruded

45
Q

What are radicular cysts?

A

True epithelium lined cyst
-Associated w/ non-vital tooth
-Most common oral cyst
-Result of proliferation of rest of Malassez
-Usually asymptomatic

46
Q

What are residual cysts?

A

Form after tooth extraction and all or part of radicular cyst is left behind

47
Q

What are some causes of external tooth resorption?

A

Inflammation
Pressure
Reimplantation
Idiopathic

48
Q

Causes of internal root resorption

A

Associated with inflammatory response in the pulp or idiopathic reason

49
Q

How is tooth resorption treated?

A

If root is not perforatied, calcium hydroxide is placed and endodontic treatment is performed to attempt to save the tooth

If root is perforated it must be removed