Infectious Disease

Question 1

HPV has a predilection to infect this type of tissue

Answer 1

stratified squamous epithelium

This is found in: true vocal cords, cervix, and anus

Question 2

HPV infection in neonates

Answer 2

Respiratory papillomatosis –> weak cry, hoarseness, stridor (infection of true vocal cords)

Question 3

HBsAg

Answer 3

Marker of acute HepB

Question 4

HBeAg

Answer 4

Marker of viral replication and increased infectivity

Question 5

HBcIgM

Answer 5

Most sensitive marker for acute HepB

Question 6

Anti HBe

Answer 6

cessation of viral replication and low infectivity

Question 7

HHV-6

Answer 7

Roseola
High fever
trunk rash

Question 8

Viruses capable of genetic reassortment with other strains

Answer 8

Orthomyxo (flu) and rotavirus both have segmented genomes

Question 9

Q fever

Answer 9

Fever lasting longer than 10 days, retroorbital HA, pneumonia, thrombocytopenia

Cattle or sheep exposure

Question 10

Vitamin that should be supplemented in measles

Answer 10

Vit A

Question 11

E coli virulence factors

Answer 11

LPS: shock
K1 capsule: prevents phagocytosis, associated with neonatal meningitis
Verotoxin: shiga like toxin in EHEC
Heat stable and labile toxins: watery diarrhea
P fimbrae: UTIs

Question 12

Tx for H drucrei

Answer 12

Azithromycin