Endocrinology

Question 1

Inhibin B is produced by the ______ in males and has negative feed back on ___

Answer 1

Sertoli cells, FSH

Question 2

Testosterone is produced by the _____ cells in males and inhibits __

Answer 2

Leydig, LH

Question 3

Progesterone withdrawal test

Answer 3

Removal of progesterone should cause prostaglandin -production leading to:
vasoconstriction of the spiral arteries

Progesterone withdrawal also cause an increase in MMPs and apoptosis of the endometrial epithelium

Question 4

Sex hormones effect on bone growth

Answer 4

accelerate bone growth but also close growth plates

Question 5

IGF-1 (Somatomedin C) effect on bone growth

Answer 5

accelerate bone growth, levels are increased with increasing levels of growth hormone

Question 6

LH Surge

Answer 6

Causes rupture of dominant follicle

hCG can be used to mimic this effect

Question 7

Layers of the adrenal gland

Answer 7

Glomerulosa: aldosterone and mineralocorticoids
Fasciculata: glucocorticoids
Reticularis: androgens
Medulla: EPI and NE