Infectious Disease

Question 1

Cryptococcus

Answer 1

Fungal
Lungs, CNS
At risk: HIV pts
Papilledema
Dx: CT, Cryptococcal antigen, India Ink stain
Tx: AmphoB, Fluconazole

Question 2

Histoplasmosis

Answer 2

Fungal
d/t bird/bat poop
Lungs
Hilar/mediastinal lymphadenopathy
Dx: Histoplasma antigen
Tx: Itraconazole

Question 3

Pneumocystis

Answer 3

Especially in AIDS CD4+ < 200
Bilat interstitial infiltrate
Tx: Trimethoprim/sulfamethoxazole

Question 4

Rheumatic Fever

Answer 4

2wks s/p Strep pharyngitis
Jones criteria
Tx: PCN

Question 5

Botulism

Answer 5

Descending weakness/paralysis
d/t canned food, raw honey in infants
Tx: PCN, antitoxin

Question 6

Cholera

Answer 6

Profuse “rice-watery” diarrhea

Question 7

Diphtheria

Answer 7

Pharyngitis
Gray membrane
Tx: antitoxin, PCN or erythromycin

Question 8

Tetanus

Answer 8

Trismus! (lockjaw)
Contraction/spasms
d/t dirty wound
ppx: Immunization!

Question 9

TB

Answer 9

d/t mycoplasma
Night sweats, productive cough, hemoptysis
Dx: CXR, acid-fast bacillus smear, RIPE
Tx: Isoniazid + VitB6

Question 10

Toxoplasmosis

Answer 10

d/t cat poop, undercooked meat, preg
Cerebral abscess
Multiple ring-enhancing lesions

Question 11

Lyme

Answer 11

d/t deer tick in NE states
Erythema migrans
Carditis
AV Block
Bell's Palsy
Dx is clinical!
Tx: Doxycycline, amoxicillin, cerufoxime

Question 12

EBV

Answer 12

d/t Mononucleosis
In post cervical lymph nodes
Pharyngitis
Splenomegaly
Morbilliform rash c Amoxicillin/Ampicillin

Question 13

HSV

Answer 13

Painful ulcerating vesicles
Prodrome
Dx: PCR, culture, or serology
Tx: antivirals

Question 14

Herpes Zoster

Answer 14

d/t VZV
Risk: >50yo females
Dermatome - pain before rash, and post-herp neuralgia
\+Hutchingson sign
Tx: antivirals

Question 15

Measles

Answer 15

Cough, Coryza, Conjunctivitis

Koplik spots

Question 16

Mumps

Answer 16

Parotid gland swelling

Elevated amylase

Question 17

Rubella

Answer 17

Forchheimer spots

Question 18

Erythema Infectiosum

Answer 18

Slapped-cheek appearance

d/t Parvovirus B19

Question 19

Roseola

Answer 19

High fever which resolves, then rash
d/t Herpesvirus 6/7
At risk: 6mo

Question 20

HIV

Answer 20

Attacks CD4+
ASx
Dx: ELISA
Tx: Two NRTI + nNRTI

Question 21

Rocky Mountain Spotte Fever

Answer 21

d/t dog tick
Rash on wrists spreading centrally; affects palms and soles
Tx: Doxycycline

Question 22

Syphilis

Answer 22

d/t Tryponema
Painless genital ulcers + rash affecting palms and soles
Dx: Dark field microscopy, RPR, FTA, ABS
Tx: PCN