Infections Qs Flashcards

1
Q

Which abx is preferred in asplenic pts?

A

PEN V

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2
Q

PO treatment of fungal nail infection

A

Terbinafine

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3
Q

BV treatment

A

Metro 400mg bd for 7 days

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4
Q

Moderate to severe allergic rhinitis

A
  1. Intranasal CS
  • PO decongestants may provide short term relief but they can cause rebound congestion
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5
Q

Doxycycline - with or without food

A

with food to prevent stomach ulcers

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6
Q

Oxybutynin + ketoconazole =

A

increased AM SE

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7
Q

Amoxicillin + warfarin

A

Amoxicillin reduces the metabolism of warfarin = increases effect leading to higher INR and risk of bleeding

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8
Q

Amoxicillin + methotrexate =

A

increased risk of tox, amocillin reduces renal clearance

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9
Q

Rubella virus

A
  • Mild fever
  • Lymphadenopathy
  • Pink maculopapular rash – starts on face and spreads
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10
Q

Can you give aciclovir cream in pregnancy?

A

YES

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11
Q

Pseudomonas bronchiestasis treatment

A

Cipro 500mg bd for 7-14 days

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12
Q

Treatment for cellulitis in penicillin allergy

A

Clindamycin

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13
Q

Facial cellulitis

A
  1. Flucloxacillin
  2. Clari/erythro/doxy
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14
Q

Doxy - headaches

A

If you get headache at start = normal
will subside

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15
Q

Notifiable diseases

A
  • rabies
  • small pox
  • covid
  • malaria
  • food poisoning
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16
Q

Bronchitis treatment

A
  1. doxy
  2. preg: amo/ erythro
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17
Q

Scarlett fever symptoms

A
  • Sore throat
  • High fever
  • Strawberry tongue
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18
Q

Gentamicin

A
  • Broad spectrum acitivity
  • Against aerobic Gram –
  • P.aeruginosa – common in cystic fibrosis and bronchiestasis
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19
Q

Trimethoprim SE

A

Fungal overgrowth

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20
Q

metronidazole 2g PO single dose

A

BV

21
Q

Pen V main SE

A

colitis

22
Q

Macrolides main SE

A

o QT interval prolongation
o AA colitis
o Seizure
o Myasthenia gravis
o Pancreatitis

23
Q

Cephalasporin main SE

A

o Hypersenitivity
o Diarrhoea
o Vulvovaginal candidiasis
o Vomiting
o Thrombocytopenia

24
Q

Glycopeptide main SE

A
  • infusion reaction
  • red-man syndrome
  • nephrotoxicity, ototoxicity
25
Q

Aminoglycosides

A

o Ototoxicity
o Nephrotoxicity
o Thrombocytopenia
o Neuropathy
o Renal damage

26
Q

Clarithromycin - pregancy

A

AVOID
particulalry in 1st trimester

27
Q

Metronidazole - pregnancy

A

Avoid

28
Q

Chloramphenicol - pregnancy

A

Avoid
Risk of neonatal ‘grey-baby syndrome’ if USED IN THIRD TRIMESTER;

29
Q

Tetracyclines - pregnancy

A

Avoid
- effects on skeletal development
- risk of discolouration of child’s teeth in 2nd/3rd trimester!

30
Q

Aminoglycosides - pregnancy

A
  • risk of auditory or vestibular nerve damage in the infant in 2ND/3RD TRIMESTER!
31
Q

Drugs to avoid in pregnancy

Carrying mothers cannot take antibiotics

A

Clari
Metronidazole
Chloramphenicol
Tetracyclines
Aminoglycosides

32
Q

Scarlett fever treatment

A
  1. Phenoxymethylpenicillin 250mg qds for 10 days
  2. Azithromycin 300mg once daily for 5 days
33
Q

Mastitis symptoms

A
  • Burning pain in breast when breastfeeding
  • Swollen, red breasts
  • Fever
34
Q

When would you treat mastitis with ABx?

A
  • Severe
  • systemically unwell
  • nipple fissures present
  • if symptoms do not improve after 12-24 hrs of effective milk removal
  • culture indicates infections
35
Q

Mastitis treatment

A
  1. flucloxacillin
    - 10-14 days
  2. If penicllin allergy: erythromycin
    - 10-14 days
36
Q

Green sputum

A

Bacterial

37
Q

Brown sputum

A

Chronic lung disease

38
Q

White sputum

A

Allergies/ viral

39
Q

Pink frothy sputum

A

HF

40
Q

Charcoal/grey sputum

A

Smokers

41
Q

hydroxychloroquine + azithromycin

A

increased risk of CV events

42
Q

Abx that causes liver failure

A

Co-amoxiclav

43
Q

Child with otitis media

A

Otigo

44
Q
A
45
Q

diverticulitis treatment

A

co-amoxiclav 500/125mg tds for 5 days

46
Q

Infantile hypertrophic pyloris stenosis

A

risk is increased in the first 14 days after birth = erythromycin

47
Q

Pregnant woman with conjunctivitis

A

Fusidic acid

48
Q

Fexofenadine + erythromycin =

A

Increased levels of fexo
Erythro = inhibitor

49
Q

Doxycycline + Gaviscon

A

Calcium carbonate = reduces absorption of doxycyline = decreased efficacy