Infections Qs Flashcards
Which abx is preferred in asplenic pts?
PEN V
PO treatment of fungal nail infection
Terbinafine
BV treatment
Metro 400mg bd for 7 days
Moderate to severe allergic rhinitis
- Intranasal CS
- PO decongestants may provide short term relief but they can cause rebound congestion
Doxycycline - with or without food
with food to prevent stomach ulcers
Oxybutynin + ketoconazole =
increased AM SE
Amoxicillin + warfarin
Amoxicillin reduces the metabolism of warfarin = increases effect leading to higher INR and risk of bleeding
Amoxicillin + methotrexate =
increased risk of tox, amocillin reduces renal clearance
Rubella virus
- Mild fever
- Lymphadenopathy
- Pink maculopapular rash – starts on face and spreads
Can you give aciclovir cream in pregnancy?
YES
Pseudomonas bronchiestasis treatment
Cipro 500mg bd for 7-14 days
Treatment for cellulitis in penicillin allergy
Clindamycin
Facial cellulitis
- Flucloxacillin
- Clari/erythro/doxy
Doxy - headaches
If you get headache at start = normal
will subside
Notifiable diseases
- rabies
- small pox
- covid
- malaria
- food poisoning
Bronchitis treatment
- doxy
- preg: amo/ erythro
Scarlett fever symptoms
- Sore throat
- High fever
- Strawberry tongue
Gentamicin
- Broad spectrum acitivity
- Against aerobic Gram –
- P.aeruginosa – common in cystic fibrosis and bronchiestasis
Trimethoprim SE
Fungal overgrowth
metronidazole 2g PO single dose
BV
Pen V main SE
colitis
Macrolides main SE
o QT interval prolongation
o AA colitis
o Seizure
o Myasthenia gravis
o Pancreatitis
Cephalasporin main SE
o Hypersenitivity
o Diarrhoea
o Vulvovaginal candidiasis
o Vomiting
o Thrombocytopenia
Glycopeptide main SE
- infusion reaction
- red-man syndrome
- nephrotoxicity, ototoxicity
Aminoglycosides
o Ototoxicity
o Nephrotoxicity
o Thrombocytopenia
o Neuropathy
o Renal damage
Clarithromycin - pregancy
AVOID
particulalry in 1st trimester
Metronidazole - pregnancy
Avoid
Chloramphenicol - pregnancy
Avoid
Risk of neonatal ‘grey-baby syndrome’ if USED IN THIRD TRIMESTER;
Tetracyclines - pregnancy
Avoid
- effects on skeletal development
- risk of discolouration of child’s teeth in 2nd/3rd trimester!
Aminoglycosides - pregnancy
- risk of auditory or vestibular nerve damage in the infant in 2ND/3RD TRIMESTER!
Drugs to avoid in pregnancy
Carrying mothers cannot take antibiotics
Clari
Metronidazole
Chloramphenicol
Tetracyclines
Aminoglycosides
Scarlett fever treatment
- Phenoxymethylpenicillin 250mg qds for 10 days
- Azithromycin 300mg once daily for 5 days
Mastitis symptoms
- Burning pain in breast when breastfeeding
- Swollen, red breasts
- Fever
When would you treat mastitis with ABx?
- Severe
- systemically unwell
- nipple fissures present
- if symptoms do not improve after 12-24 hrs of effective milk removal
- culture indicates infections
Mastitis treatment
- flucloxacillin
- 10-14 days - If penicllin allergy: erythromycin
- 10-14 days
Green sputum
Bacterial
Brown sputum
Chronic lung disease
White sputum
Allergies/ viral
Pink frothy sputum
HF
Charcoal/grey sputum
Smokers
hydroxychloroquine + azithromycin
increased risk of CV events
Abx that causes liver failure
Co-amoxiclav
Child with otitis media
Otigo
diverticulitis treatment
co-amoxiclav 500/125mg tds for 5 days
Infantile hypertrophic pyloris stenosis
risk is increased in the first 14 days after birth = erythromycin
Pregnant woman with conjunctivitis
Fusidic acid
Fexofenadine + erythromycin =
Increased levels of fexo
Erythro = inhibitor
Doxycycline + Gaviscon
Calcium carbonate = reduces absorption of doxycyline = decreased efficacy