CV - HT Flashcards

1
Q

At what K level would you add low dose spironolactone?

A

< 4.5

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2
Q

Which antihypertensive is preferred in breastfeeding?

A

Enalapril

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3
Q

Pregnancy - HT treatment

A
  1. Labetalol
  2. MR nifedipine
  3. Methyldopa
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4
Q

When should you stop methyldopa for HT in pregnancy?

A
  • Stop at least 2 days after birth
  • Risk of post-natal depression
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5
Q

Symptoms of pre-eclampsia

A
  • Severe headache
  • Pain below ribs
  • Vision
  • Vomiting
  • Sudden swelling of face, hands, feet
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6
Q

What do we give for chronic HT in pregnancy

A
  • Aspirin 75-150mg OD
  • Week 12 to birth
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7
Q

ACEi: CI

A
  • Bilateral renal artery stenosis/ aortic stenosis
  • Pregnancy
  • AKI
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8
Q

ACEi: SE

A
  1. COUGH
  2. Renal/ hep
  3. Angiodema
  4. Hyperkalaemia
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9
Q

ACEi: interactions

A
  1. ARBs
  2. K
  3. Lithium
  4. NSAIDs - renal
  5. Alcohol
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10
Q

ARBs: SE

A
  1. Hyperkalaemia
  2. Hypotension
  3. Renal

less cough and angiodema

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11
Q

CCB: RL

A
  • Highly inotropic effects =
  • Reduced myocontractility + HR
  • Avoid in HF
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12
Q

Which antihypertensive should we avoid in HF?

A

RL CCB

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13
Q

CCB: dihydro SE

A
  • oedema
  • headache
  • flushing
  • constipation
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14
Q

CCB: interactions

A
  1. Statins: sim + amlo
  2. Dabigatran + verapamil
  3. BB + verapamil
  4. Carbamazepine
  5. Grapefruit juice
  6. Macrolides
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15
Q

Does diltiazem need to be prescribed by brand?

A

Only for dilt MR tabs with strength over 60mg

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16
Q

Does nifedipine need to be prescribed by brand?

A

For MR yes - no matter what strength

17
Q

TLD: duration

A

act: 1-2 hrs
last: 12-24 hrs

18
Q

TLD: CI

A

Hypokalaemia - risk of cardiac arrythmias

19
Q

Which TLD has risk of non melanoma skin cancer with long term use?

A

Hydrochlorothiazide

20
Q

TLD: SE

A
  • Gout
  • Hyperglycaemia
  • HypoK, Na
  • HyperCa
  • Postural hypotension
21
Q

TLD: interactions

A
  • Lithium
  • Digoxin
  • NSAIDs
22
Q

Loop: onset

A

1hr, diuresis complete within 6hrs
Can give BD if needed w/o interupting sleep

23
Q

Loop: SE

A
  • Gout
  • Hyperglycaemia
  • HypoK, Na, Ca
  • Postural hypotension
  • Oto
24
Q

How to remember the electrolyte difference between TLD and loop

A

Only difference is Ca
TLD = high
Loop = low

25
Q

Loop: interactions

A
  • Lithium
  • Digoxin
  • NSAID
  • AG - oto