Infection Qs 2 Flashcards

1
Q

Bites treatment

A
  1. Co-amoxiclav
  2. Doxycycline + metronidazole

5 days

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2
Q

Lyme disease treatment

A
  1. Doxycycline (100mg BD)
  2. Amoxicillin
  3. Azithromycin
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3
Q

Mastitis treatment

A
  1. Flucloxacillin
  2. Erythromycin

10-14 days

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4
Q

When do you treat mastitis with Abx?

A
  • Severe
  • Systemically unwell
  • Nipple fissure
  • Symptoms do not improve after 12-24h of effective milk removal
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5
Q

Can you continue breastfeeding during treatment for mastitis?

A

Yes

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6
Q

Human/ animal scratches treatment

A

Flucloxacillin

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7
Q

Cellulitis treatment

A
  1. Flucloxacillin 0.5-1g QDS
  2. Clarithromycin/ erythromycin
  3. Doxycyline

5-7 days

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8
Q

Cellulitis near eyes/ nose treatment

A
  1. Co-Amoxiclav 625mg TDS for 7 days
  2. Clarithromycin 500mg BD + Metronidazole 400mg TDS for 7 days
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9
Q

CAP treatment:
Low severity (0)

A
  1. Amoxicillin
  2. Clarithromycin
  3. Doxycyline

5 days

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10
Q

CAP treatment:
Mod severity (1-2)

A
  1. Amoxicillin + clarithromycin/ erythromycin
  2. Clarithromycin
  3. Doxycycline

5 days

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11
Q

CAP treatment:
High severity (3+)

A
  1. Co-amoxiclav + clarithromycin/ erythromycin
  2. Levofloxacin

5 days

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12
Q

Diabetic foot infection treatment
Mild infection

A
  1. Flucloxacillin 500mg-1g QDS
  2. Clarithromycin / Erythromycin (pregnancy) / Doxycycline

7 days

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13
Q

Diabetic foot infection treatment
Moderate/severe infection

A
  1. Flucloxacillin +/ - IV Gentamicin and/or metronidazole
    or
    Co-trimoxazole +/ - IV Gentamicin and/or metronidazole
  2. Co-amoxiclav +/- IV gentamicin
  3. IV ceftriaxone with metronidazole
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14
Q

Diabetic foot infection treatment
Moderate/severe infection
Pseudomonas aeruginosa suspected or confirmed

A
  1. IV piperacillin with tazobactam
  2. Clindamycin with ciprofloxacin and/or IV gentamicin
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15
Q

Diabetic foot infection treatment
Moderate/severe infection
MRSA suspected or confirmed

A
  • IV vancomycin
  • IV teicoplanin
  • linezolid
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16
Q

1st episode of C.diff

A
  1. Vancomycin 125 mg QDS
  2. Fidoxamicin 200 mg BD

10 days

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17
Q

C.diff treatment
Further episode within 12 weeks (relapse)

A

Fidoxamicin

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18
Q

C.diff treatment
Further episode after 12 weeks (recurrence)

A

Vancomycin or fidoxamicin

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19
Q

Life-threatening C.diff treatment

A

Vancomycin 500 mg QDS AND Metronidazole 500 mg IV TDS

10 days

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20
Q

Otitis media treatment: non abx

A
  1. Paracetamol/ ibuprofen
  2. Otigo
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21
Q

Otitis media treatment: abx

A
  1. Amoxicillin
  2. No improvement = co-Amoxiclav
  3. Clarithromycin (Erythromycin in pregnancy)

5-7 days

22
Q

Otitis externa treatment

A
  1. Topical Acetic Acid 2%
  2. Topical Neomycin Sulphate with Corticosteroid
  3. If systemic treatment needed: Flucloxacillin
23
Q

HAP treatment

A
  1. Co-Amoxiclav
  2. Doxycycline/ Cefalexin/ Co-trimoxazole [unlicensed]/ Levofloxacin [unlicensed]
    SECOND (children): Clarithromycin
24
Q

HAP severe treatment

A

IV FIRST LINE:
Piperacillin with tazobactam
ceftazidime
ceftazidime with avibactam, - ceftriaxone
cefuroxime
levofloxacin [unlicensed]
or meropenem.

25
Q

Impetigo
Treatment for Localised non-bullous

A
  1. Hydrogen peroxide 1% cream 2-3 times a day for 5-7 days
  2. Fusidic Acid for 5 days
  3. Mupirocin 2%
26
Q

Impetigo
Widespread non-bullous: treatment

A
  1. Fusidic acid
  2. Mupirocin
27
Q

Impetigo
Bullous or systemically unwell

A
  1. Flucloxacillin 500mg QDS
  2. Clarithromycin 250mg BD/ Erythromycin 250-500mg QDS

5 days

28
Q

UTI treatment
non-pregnant woman

A
  1. Nitrofurantoin or trimethoprim
  2. Pivmecillinam/ fosfomycin/ amoxicillin

3 days

29
Q

UTI treatment
Pregnant woman

A
  1. Nitrofurantoin
  2. Cefalexin/ amoxicillin

7 days

30
Q

UTI prophylaxis dose

A

50-100 mg nocte
100mg trigger exposure

31
Q

UTI treatment
men

A
  1. Nitro/trim
  2. No improvement in 48hrs = consider pyelo/ prostatitis
32
Q

Meningitis treatment: during transfer to hospital

A
  1. Benzylpenicillin
  2. Chloramphenicol
33
Q

Meningitis treatment:
in hospital

A
  1. Ceftriaxone/cefotaxime
34
Q

Meningitis treatment:
in hospital
aetiology unknown: adult 60 +

A
  1. cefotaxime (or ceftriaxone) + amoxicillin (or ampicillin)
  2. consider vancomycin

10 days

35
Q

Billiary-tract infection treatment

A

Ciprofloxacin
OR
Gentamicin
OR
Cephalosporin

36
Q

Peritonitis treatment

A

Cephalosporin + Metronidazole
OR
Gentamicin + Metronidazole
OR
Gentamicin + Clindamycin
OR
Pip w taz

37
Q

Typhoid fever treatment

A
  1. Cefotaxime (or Ceftriaxone)
  2. Azithromycin or
    Ciprofloxacin
38
Q

Shigellosis treatment

A
  1. Ciprofloxacin OR Azithromycin
  2. Alternative if micro-organism sensitive:
    Amoxicillin OR
    Trimethoprim
39
Q

Salmonella treatment

A
  1. Cipro
  2. Cefotaxime
40
Q

Campylobacter enteritis treatment

Food poisoning

A
  1. Clarithromycin (or Azithro or Erythro)
  2. Ciprofloxacin
41
Q

CA septicaemia treatment

A

broad spectrum anti-psuedomonal penicillin
e.g. piperacillin with tazobactam
e.g. ticaricillin with clavulanic acid

42
Q

HA septicaemia treatment

A

Broad spectrum anti psuedomonal beta lactic abx
- piperacillin with tazobactam,
- ticarcillin with clauvulanic acid
- ceftazidime
- imipenem with cilastatin
- meropenem

43
Q

Blind therapy endocarditis
Native heart valve

A
  1. Amoxicillin (or ampicillin) - May consider adding low-dose gentamicin
    2.penicillin allergy/MRSA = vancomycin + low dose gentamicin
    3.Staphlococci = flucloxacillin for 4 weeks, if penicillin allergy/ MRSA= vancomycin + rifampicin for 4 weeks
44
Q

Blind therapy endocarditis
Prosthetic heart valve

A

1.Vancomycin + rifampacin +
low-dose Gentamicin
2.Staphlococci = flucloxacillin + rifampicin + low dose gentamicin (at least 6 weeks, review gentamicin after 2)
3.Penicillin allergy/MRSA= Vancomycin + Rifampacin + Low-dose Gentamicin

45
Q

How long is the treatment for native or prosthetic heart valve endocarditis?

A

4 weeks for native
6 weeks for prosthetic

46
Q

Sepsis 6

A

Treatment (3)
1. Abx - broad at max dose within 1 hour of diagnosis. Narrow once blood culture tests are done
2. IV fluids (for fluid resuscitation)
3. Oxygen (give oxygen)

Tests (3)
4. Blood culture
5. Blood tests (including lactate)
6. Monitor urine output

47
Q

Epiglottis treatment

A
  1. Cefotaxime (or
    Ceftriaxone)
  2. Chloramphenicol
48
Q

Acute exacerbations of chronic bronchitis treatment

A
  1. Amoxicillin (or Ampicillin)
    OR
  2. Tetracycline

Both for 5 days (longer if serious illness)

49
Q
A
50
Q

Treatment of recurrent aphthous ulceration

A

Doxy 100mg dispersible tablets qds for 3 days to be used as mouthwash and not swallowed