Infection Qs 2 Flashcards
Bites treatment
- Co-amoxiclav
- Doxycycline + metronidazole
5 days
Lyme disease treatment
- Doxycycline (100mg BD)
- Amoxicillin
- Azithromycin
Mastitis treatment
- Flucloxacillin
- Erythromycin
10-14 days
When do you treat mastitis with Abx?
- Severe
- Systemically unwell
- Nipple fissure
- Symptoms do not improve after 12-24h of effective milk removal
Can you continue breastfeeding during treatment for mastitis?
Yes
Human/ animal scratches treatment
Flucloxacillin
Cellulitis treatment
- Flucloxacillin 0.5-1g QDS
- Clarithromycin/ erythromycin
- Doxycyline
5-7 days
Cellulitis near eyes/ nose treatment
- Co-Amoxiclav 625mg TDS for 7 days
- Clarithromycin 500mg BD + Metronidazole 400mg TDS for 7 days
CAP treatment:
Low severity (0)
- Amoxicillin
- Clarithromycin
- Doxycyline
5 days
CAP treatment:
Mod severity (1-2)
- Amoxicillin + clarithromycin/ erythromycin
- Clarithromycin
- Doxycycline
5 days
CAP treatment:
High severity (3+)
- Co-amoxiclav + clarithromycin/ erythromycin
- Levofloxacin
5 days
Diabetic foot infection treatment
Mild infection
- Flucloxacillin 500mg-1g QDS
- Clarithromycin / Erythromycin (pregnancy) / Doxycycline
7 days
Diabetic foot infection treatment
Moderate/severe infection
- Flucloxacillin +/ - IV Gentamicin and/or metronidazole
or
Co-trimoxazole +/ - IV Gentamicin and/or metronidazole - Co-amoxiclav +/- IV gentamicin
- IV ceftriaxone with metronidazole
Diabetic foot infection treatment
Moderate/severe infection
Pseudomonas aeruginosa suspected or confirmed
- IV piperacillin with tazobactam
- Clindamycin with ciprofloxacin and/or IV gentamicin
Diabetic foot infection treatment
Moderate/severe infection
MRSA suspected or confirmed
- IV vancomycin
- IV teicoplanin
- linezolid
1st episode of C.diff
- Vancomycin 125 mg QDS
- Fidoxamicin 200 mg BD
10 days
C.diff treatment
Further episode within 12 weeks (relapse)
Fidoxamicin
C.diff treatment
Further episode after 12 weeks (recurrence)
Vancomycin or fidoxamicin
Life-threatening C.diff treatment
Vancomycin 500 mg QDS AND Metronidazole 500 mg IV TDS
10 days
Otitis media treatment: non abx
- Paracetamol/ ibuprofen
- Otigo
Otitis media treatment: abx
- Amoxicillin
- No improvement = co-Amoxiclav
- Clarithromycin (Erythromycin in pregnancy)
5-7 days
Otitis externa treatment
- Topical Acetic Acid 2%
- Topical Neomycin Sulphate with Corticosteroid
- If systemic treatment needed: Flucloxacillin
HAP treatment
- Co-Amoxiclav
- Doxycycline/ Cefalexin/ Co-trimoxazole [unlicensed]/ Levofloxacin [unlicensed]
SECOND (children): Clarithromycin
HAP severe treatment
IV FIRST LINE:
Piperacillin with tazobactam
ceftazidime
ceftazidime with avibactam, - ceftriaxone
cefuroxime
levofloxacin [unlicensed]
or meropenem.
Impetigo
Treatment for Localised non-bullous
- Hydrogen peroxide 1% cream 2-3 times a day for 5-7 days
- Fusidic Acid for 5 days
- Mupirocin 2%
Impetigo
Widespread non-bullous: treatment
- Fusidic acid
- Mupirocin
Impetigo
Bullous or systemically unwell
- Flucloxacillin 500mg QDS
- Clarithromycin 250mg BD/ Erythromycin 250-500mg QDS
5 days
UTI treatment
non-pregnant woman
- Nitrofurantoin or trimethoprim
- Pivmecillinam/ fosfomycin/ amoxicillin
3 days
UTI treatment
Pregnant woman
- Nitrofurantoin
- Cefalexin/ amoxicillin
7 days
UTI prophylaxis dose
50-100 mg nocte
100mg trigger exposure
UTI treatment
men
- Nitro/trim
- No improvement in 48hrs = consider pyelo/ prostatitis
Meningitis treatment: during transfer to hospital
- Benzylpenicillin
- Chloramphenicol
Meningitis treatment:
in hospital
- Ceftriaxone/cefotaxime
Meningitis treatment:
in hospital
aetiology unknown: adult 60 +
- cefotaxime (or ceftriaxone) + amoxicillin (or ampicillin)
- consider vancomycin
10 days
Billiary-tract infection treatment
Ciprofloxacin
OR
Gentamicin
OR
Cephalosporin
Peritonitis treatment
Cephalosporin + Metronidazole
OR
Gentamicin + Metronidazole
OR
Gentamicin + Clindamycin
OR
Pip w taz
Typhoid fever treatment
- Cefotaxime (or Ceftriaxone)
- Azithromycin or
Ciprofloxacin
Shigellosis treatment
- Ciprofloxacin OR Azithromycin
- Alternative if micro-organism sensitive:
Amoxicillin OR
Trimethoprim
Salmonella treatment
- Cipro
- Cefotaxime
Campylobacter enteritis treatment
Food poisoning
- Clarithromycin (or Azithro or Erythro)
- Ciprofloxacin
CA septicaemia treatment
broad spectrum anti-psuedomonal penicillin
e.g. piperacillin with tazobactam
e.g. ticaricillin with clavulanic acid
HA septicaemia treatment
Broad spectrum anti psuedomonal beta lactic abx
- piperacillin with tazobactam,
- ticarcillin with clauvulanic acid
- ceftazidime
- imipenem with cilastatin
- meropenem
Blind therapy endocarditis
Native heart valve
- Amoxicillin (or ampicillin) - May consider adding low-dose gentamicin
2.penicillin allergy/MRSA = vancomycin + low dose gentamicin
3.Staphlococci = flucloxacillin for 4 weeks, if penicillin allergy/ MRSA= vancomycin + rifampicin for 4 weeks
Blind therapy endocarditis
Prosthetic heart valve
1.Vancomycin + rifampacin +
low-dose Gentamicin
2.Staphlococci = flucloxacillin + rifampicin + low dose gentamicin (at least 6 weeks, review gentamicin after 2)
3.Penicillin allergy/MRSA= Vancomycin + Rifampacin + Low-dose Gentamicin
How long is the treatment for native or prosthetic heart valve endocarditis?
4 weeks for native
6 weeks for prosthetic
Sepsis 6
Treatment (3)
1. Abx - broad at max dose within 1 hour of diagnosis. Narrow once blood culture tests are done
2. IV fluids (for fluid resuscitation)
3. Oxygen (give oxygen)
Tests (3)
4. Blood culture
5. Blood tests (including lactate)
6. Monitor urine output
Epiglottis treatment
- Cefotaxime (or
Ceftriaxone) - Chloramphenicol
Acute exacerbations of chronic bronchitis treatment
- Amoxicillin (or Ampicillin)
OR - Tetracycline
Both for 5 days (longer if serious illness)
Treatment of recurrent aphthous ulceration
Doxy 100mg dispersible tablets qds for 3 days to be used as mouthwash and not swallowed