Immunosuppresion + chemotherapy Flashcards
1
Q
cytotoxic drugs which formulations are not interchangeable
A
Paclitaxel
2
Q
Which drugs are least likely to cause bone marrow suppression?
A
Vincristine and bleomycin
3
Q
Low emetogenic drugs
A
- Florouracil
- Etoposide
- Methotrexate (Low dose)
- Vinca-alkaloids
- Abdominal radiotherapy
4
Q
Moderate emetogenic drugs
A
- Taxanes
- Doxorubicin
- Low/intermediate dose of
Cyclophosphamide
5
Q
High emetogenic drugs
A
- Cisplatin
- Dacarbazine
- High doses of cyclophosphamide
6
Q
Which drug causes pulmonary fibrosis?
A
Cytotoxic abx e.g. bleomycin
7
Q
Vinca alkaloids SE
A
- peripheral paraesthesia
- loss of tendon reflex
- abdo pain and constipation
8
Q
Bin colours
A
Blue - empty and part used bottles, vials, tubes
Purple - cytotoxic waste
9
Q
Cisplatin and electrolyte disturbance =
A
hypomagnesaemia so pt is also routinely prescribed magnesium satchets to mairain levels
